8 results
Causes of blood culture negative infective endocarditis

Bartonella spp, Brucella spp, Coxiella burnetii, Chlamydia spp, Tropheryma whipplei,
Causes of blood ... culture negative ... Tropheryma whipplei, Fungi ... #culture #negative ... InfectiousDiseases #Microbiology
Blood Culture-Negative Infective Endocarditis (BCNIE)
Definition: No etiology found after 3 separate blood cultures remain negative for
Blood Culture-Negative ... cultures remain negative ... fastidious bacteria or fungi ... but important causes ... Tropheryma whipplei, Fungi
Important Fungal Stains
Mycology Lab:
 • Calcofluor white - Fluorochrome that binds glucans and chitin in fungal
Important Fungal ... • India ink - "Negative ... #microbiology #microscopy ... #fungus #comparison ... #table
Approach to Eosinophilic Lung Diseases
 • Acute Eosinophilic Pneumonia (< 1 wk) - ~30yo, M; Recent
, CNS, skin • Infectious ... (Variable) - Fungal ... Lung #Diseases #pulmonary ... differential #diagnosis #comparison ... #table #eosinophilia
Differentiating NBTE from Infective Endocarditis
No pathognomonic signs/symptoms or echo features that are specific to NBTE, and
Frequent false-negative ... in up to 30% of cases ... large infarct - Infectious ... #Endocarditis #comparison ... Marantic #diagnosis #table
Endocarditis Summary

Who?
Infectious:
• Pre-existing valvular disease
• Prosthetic valve
• Congenital heart disease
• IV substance use
• IV catheter
• Recent
Infectious: • Pre-existing ... Hypercoagulable (APLAS) Microbiology ... • Coagulase-negative ... Cerebral > Splenic, pulmonary ... Septic Emboli Cause
Lung Abscess - Diagnosis and Management Summary

Lung Abscess Etiology:
 • Necrosis of lung parenchyma by a
polymicrobial infection ... • Most common cause ... Prevotella • Fungal ... Lung #Abscess #pulmonary ... #differential #causes
Endocarditis - Overview and Differential Diagnosis Framework

Who?
Infectious:
• Pre-existing valvular disease
• Prosthetic valve
• Congenital heart disease
• IV
Hypercoagulable (APLAS) Microbiology ... aureus, Coagulase-negative ... staphylococci Culture Negative ... Cerebral > Splenic, Pulmonary ... Septic emboli cause