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diagnosis differential management activetb latenttb tuberculosis infections treatment workup active bcnie bloodculture causes chondrocalcinosis fever fungal gout hemoptysis intermittent latent
Fever Patterns - Differential Diagnosis Framework Continuous Fever: Temp > 38°C with only 1 degree fluctuation in 24
• Typhus, gram-negative ... Pyogenic/focal infection ... • Lymphoma • TB ... arthritis • Infective ... Night Sweats: • TB
Differentiating NBTE from Infective Endocarditis No pathognomonic signs/symptoms or echo features that are specific to NBTE, and
Differentiating NBTE from Infective ... serology: Serial negative ... Frequent false-negative ... - Infectious Diseases ... #comparison #infective
Tuberculosis Testing LATENT TB • LTBI is diagnosed when an asymptomatic patient has a positive TST or IGRA
developing active infection ... intermediate risk of disease ... • Tuberculosis infection ... because false-negative ... LatentTB #ActiveTB #InfectiousDiseases
CPPD vs Gout == CPPD == Think About CPPD When: • Self-limited synovitis after surgery/trauma (> 65
• Underlying disease ... states Pathophysiology ... diagnose concomitant infection ... Needle-shaped, negatively ... #Gout #Comparison
Blood Culture-Negative Infective Endocarditis (BCNIE) Definition: No etiology found after 3 separate blood cultures remain negative for
Blood Culture-Negative ... Infective Endocarditis ... exists Infectious Diseases ... #Infective #Endocarditis ... differential #workup #infectiousdiseases
Tuberculosis Overview 10 million new M. tuberculosis infections/year Facultative intracellular rod-shaped bacteria Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
tuberculosis (LTBI) Pathophysiology ... HIV • Recent infection ... mycobacterial infection ... NTM) • Fungal infection ... assay (IGRA) • PPD
Tuberculosis Overview 10 million new M. tuberculosis infections/year Facultative intracellular rod-shaped bacteria Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
tuberculosis (LTBI) Pathophysiology ... HIV • Recent infection ... mycobacterial infection ... NTM) • Fungal infection ... assay (IGRA) • PPD
Hemoptysis - Differential Diagnosis Framework Massive Hemoptysis: >150-300 mL in 24h Airway disease: • Bronchitis, Bronchiectasis, Malignancy
in 24h Airway disease ... carcinoid, Mets), COPD ... Parenchyma: • Infection ... : Bacterial (TB, ... regurgitation, Tricuspid endocarditis
Pseudogout: pathogenesis and clinical findings - Idiopathic (vast majority of cases) -> Mechanism unknown - Familial
Hypomagnesia -> The relative ... Hypophosphatasia -> Defective ... and/or x-ray - CPPD ... #Disease #Signs ... #Symptoms #Pathophysiology
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
monophasic Pathophysiology ... Direct microbial infection ... tested and if negative ... , Hep A/B/CMV, TB ... MCTD - Bechet disease
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