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diagnosis pharmacology antibiotics overview review active anticholinergics aztreonam cardiology chloramphenicol clozapine cppd diabetes diabetic differential dka edema endocrinology gout hyperglycemic
Pathophysiology of Diabetic Ketoacidosis (DKA) and Hyperglycemic Hyperosmolar Syndrome (HHS) Absolute Insulin deficit: - Type I DM:
Pathophysiology ... Hyperosmolar Syndrome (HHS ... insulin demand Relative ... #pathophysiology ... #comparison #endocrinology
Toxidromes Compared: Anticholinergic, Cholinergic, Opioid, Sympathomimetic, Sedative-Hypnotic During your physical exam, look for evidence of some of
Sympathomimetic, Sedative-Hypnotic ... acute cholinergic toxicity ... Opioid toxicity ... #Diagnosis #Toxicology ... #Toxidromes #Comparison
Tuberculosis Testing LATENT TB • LTBI is diagnosed when an asymptomatic patient has a positive TST or IGRA
asymptomatic patient has ... testing (TST) False-negative ... because false-negative ... sample = 95% • A negative ... #InfectiousDiseases
Clozapine Toxicology Clozapine is an atypical antipsychotic most often reserved for use in patients who have treatment-resistant
Clozapine Toxicology ... effect on negative ... some limited activity ... #Clozapine #Toxicology ... #Toxicity #Diagnosis
Metformin Associated Lactic Acidosis (MALA) Pathophysiology of MALA - Metformin interferes with the activity of the
Acidosis (MALA) Pathophysiology ... interferes with the activity ... LacticAcidosis #Toxicity ... #Toxicology #Diagnosis
Noncardiogenic Pulmonary Edema - Differential Diagnosis Framework NCPE Pathophysiology: Noncardiogenic pulmonary edema occurs because of excessive pulmonary capillary
Framework NCPE Pathophysiology ... renin-angiotensin-aldosterone system activity ... • Normal or negative ... • Salicylate toxicity ... hemorrhage, seizure activity
Monobactam - Aztreonam - Antibiotics Class Overview Spectrum: only has activity vs. aerobic gram negatives, no gram
Spectrum: only has ... activity vs. aerobic ... gram negatives, ... anaerobes (similar activity ... no significant toxicity
CPPD vs Gout == CPPD == Think About CPPD When: • Self-limited synovitis after surgery/trauma (> 65
disease states Pathophysiology ... deposit and can activate ... Think of the "H's ... Needle-shaped, negatively ... #CPPD #Gout #Comparison
Chloramphenicol - Antibiotics Class Overview – 50S ribosomal inhibitor. IV or PO (but PO form
E.faecium/VRE); Gram negatives ... due to potential toxicity ... beta-lactam allergy (has ... activity vs S.pneumo ... appropriate patients) - Toxicity
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