58 results
Approach to Thrombotic Microangiopathy (TMA) - Differential Diagnosis and Management Algorithm

Suspected TMA: Unexplained thrombocytopenia + MAHA
- Differential Diagnosis ... and Management ... Initial labs: CBC ... normal • DAT negative ... #hematology
Suggested algorithm for follow-up of monoclonal gammopathy of undetermined significance (MGUS)
Mayo Clinic Risk Stratification Model. CBC,
significance (MGUS) Mayo Clinic ... CBC, complete blood ... Followup #algorithm #diagnosis ... #management #hematology
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
three primary pathophysiologic ... With associated pulmonary ... Pauci-immune mediated (Negative ... #differential #diagnosis ... #algorithm #rheumatology
C.diff - Clostridioides Difficile Infection (CDI) - Diagnosis and Management - GrepMed Handbook

Clinical Presentation + Progression:
Management - GrepMed ... Handbook Clinical ... Perforation) Pathophysiology ... #management #treatment ... #infectiousdiseases
Bullous Pemphigoid - Diagnosis and Management Summary
Pathophysiology: Autoantibody-mediated damage to epithelial basement membrane -> separation of
Bullous Pemphigoid - Diagnosis ... Summary Pathophysiology ... epidermis from dermis Clinical ... not feasible CMC ... #Management #dermatology
Pott's Disease in Tuberculosis - Diagnosis and Management Summary
Epidemiology:
 - Typically from TB endemic areas
 -
extrapulmonary cases Clinical ... symptoms of active pulmonary ... decreased reflexes Pathophysiology ... for concomitant pulmonary ... intervention CMC
Tuberculosis Testing

LATENT TB
• LTBI is diagnosed when an asymptomatic patient has a positive TST or IGRA
result with no clinical ... because false-negative ... sample = 95% • A negative ... used to exclude pulmonary ... LatentTB #ActiveTB #InfectiousDiseases
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Erythematosus (SLE) - Diagnosis ... 40, F:M 9:1 • Clinical ... pANCA anti-MPO - Negative ... Erythematosus #Diagnosis ... #rheumatology
Bandemia Overview

Normal: < 1%
Clinically significant: > 10%

Band neutrophils are slightly less mature than segmented neutrophils and
Normal: < 1% Clinically ... likelihood of negative ... clinical outcomes ... neutrophil #WBC #CBC ... #hematology #pathophysiology
Algorithm for Management of Acute Exacerbation of COPD (AECOPD)

Obtain workup for alternate diagnoses and relevant comorbidities:
Algorithm for Management ... for alternate diagnoses ... comorbidities: • CBC ... of AECOPD: • Clinical ... Exacerbation #treatment #pulmonary