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differential management hematology arthritis gout joint pain signs workup agglutinin ana anemia antinuclear approach autoantibodies autoimmune behcet causes celiac chronic
Causes of Knee Effusions - Differential Diagnosis Framework Knee Effusion Red Flags: 1. Fever/Chills/Joint pain/Night sweats/Weight loss - DDX: -
- Differential Diagnosis ... Osteoarthritis - Overuse syndrome ... Seronegative Reactive Syndrome ... #differential #diagnosis ... #msk #physicalexam
Meralgia paresthetica: Pathogenesis and Clinical Findings Compression/injury of Lateral Femoral Cutaneous Nerve (LFCN) -> Meralgia paresthetica •
sensory • Before diagnosis ... intervertebral disc disease ... Stabbing) - Negative ... Straight Leg Raise Test ... MeralgiaParesthetica #MSK
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
meningitis), MCC CNS symptoms ... Positive pathergy test ... is a skin prick test ... #signs #symptoms ... #rheumatology #
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Cold Agglutinin Syndrome ... for anti-C3d and negative ... Test: Donath-Landsteiner ... test #cold # ... hemolytic #anemia #hematology
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
Cryofibrinogenemia Symptoms ... levels >1g/L • Negative ... cryoglobulins • Negative ... Antiphospholipid syndrome ... #rheumatology #
Approach to Joint Pain History: Is the pain from: • Joint • Adjacent bursa • Tendon • Ligament • Bone • Muscle • Referred from
or nerve root Symptoms ... of Joint Disease ... #Joint #Pain #MSK ... #rheumatology # ... #differential #diagnosis
Antinuclear antibodies and Systemic lupus Anti-dsDNA 60-80% Association with disease activity (when with Farr assay) and lupus nephritis. Can
clinically suspected, tests ... SLE-SSc-AlM overlap syndromes ... Negative association ... erythematosus #diagnosis ... #rheumatology #
Approach to Joint Pain - Arthritis Differential Diagnosis Framework Inflammatory Versus Noninflammatory Pain • Is it inflammatory
Arthritis Differential Diagnosis ... constitutional symptoms ... aureus • Gram-negative ... #Differential #Diagnosis ... #MSK #rheumatology
SAPHO Syndrome Summary What? SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
affected areas and if negative ... blockers had the best ... osteoarticular and skin disease ... #Rheumatology # ... diagnosis #management
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
- Differential Diagnosis ... • Cogan Syndrome ... Presentation - Systemic Symptoms ... retinopathy Lab Tests ... #rheumatology #
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