12 results
Approach to Thrombotic Microangiopathy (TMA) - Differential Diagnosis and Management Algorithm

Suspected TMA: Unexplained thrombocytopenia + MAHA
- Differential Diagnosis ... and Management ... Direct antiglobulin test ... normal • DAT negative ... #hematology
Disseminated Gonococcal Infection - Diagnosis and Management Summary

Bacteremic spread of the Gram-negative diplococci Neisseria gonorrhoeae. History
and Management ... spread of the Gram-negative ... the preferred test ... typically part of the workup ... • Test all patients
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura

Activity of von Willebrand factor-cleaving protease activity - A
activity is the diagnostic ... value is low, tests ... indirect antiglobulin tests ... - Negative, ruling ... #Workup #Hematology
IgG4-Related Disease
Clinical history:  Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor
4 phenotypes:
 •
• Some false negative ... specific laboratory tests ... #management #phenotypes ... #workup #treatment ... #rheumatology
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
affected areas and if negative ... blockers had the best ... #Rheumatology # ... diagnosis #management ... #Dermatology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Macrophage Activation Syndrome ... Periodic fever syndromes ... Liver function tests ... #Diagnosis #Management ... #Hematology #Rheumatology
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Cold Agglutinin Syndrome ... for anti-C3d and negative ... Test: Donath-Landsteiner ... test #cold # ... hemolytic #anemia #hematology
Polycythemia - Differential Diagnosis Algorithm
Polycythemia itself isn’t a diagnosis. Like many things, it is a condition
Better call hematology ... you’ll do a good workup ... Best to have an ... #Algorithm #workup ... #hematology
Acromegaly - Diagnosis and Management Summary - GrepMed Handbook 

Clinical Presentation: 
 • Classic Acromegaly: frontal
and Management ... paresthesias (carpal tunnel ... Beckwith Wiedemann syndrome ... and Workup: • ... glucose suppression test
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
adults in the west ... phenomenon CLL Diagnosis ... • Richter’s Syndrome ... #workup #oncology ... #hematology