34 results
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
pylori test (GI symptoms ... (CVID, WAS), (neurologic ... changes), high MCV anemia ... #Causes #Workup ... #hematology
Gastrointestinal Evaluation of Iron Deficiency Anemia
In patients with anemia, diagnose iron deficiency if:
 • Ferritin <
, diagnose iron ... Test for celiac disease ... endoscopy only if: • Negative ... Gastrointestinal #Evaluation #workup ... #diagnosis #gastroenterology
Multiple Myeloma and Monoclonal Gammopathies
C - HyperCalcemia- calcium > 11 mg/dL / >1 mg/dL the ULN
R
40 ml/min A - Anemia ... Causes of false- ... negative SPEP: ... Gammopathies #MGUS #diagnosis ... #hematology #oncology
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
of anemia include ... anemia • Cold ... for anti-C3d and negative ... #hemolytic #anemia ... #hematology #diagnosis
Causes of Polycythemia (Erythrocytosis) - Differential Diagnosis Algorithm
Relative - Normal RBC Mass / Decreased Plasma Volume
Causes of Polycythemia ... - Differential Diagnosis ... Algorithm Relative ... Chronic Chest Symptoms ... #Hematology
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura

Activity of von Willebrand factor-cleaving protease activity - A
hallmark for the disease ... result in severe anemia ... antiglobulin tests - Negative ... immune hemolytic anemia ... #Workup #Hematology
Causes of Secondary Hypertension - Workup and Differential Diagnosis
Approach (when evaluation should be done):
1. Severe or
Hypertension - Workup ... and Differential Diagnosis ... patients with a negative ... Renal parenchymal disease ... Neurologic disorders
Bandemia Overview

Normal: < 1%
Clinically significant: > 10%

Band neutrophils are slightly less mature than segmented neutrophils and
Differential Diagnosis ... • Autoimmune diseases ... likelihood of negative ... neutrophil #WBC #CBC #hematology ... #pathophysiology
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
65 years PBC Pathophysiology ... intralobular bile ducts causes ... PBC Signs and Symptoms ... but elevated as disease ... #workup #hepatology
Differentiating NBTE from Infective Endocarditis
No pathognomonic signs/symptoms or echo features that are specific to NBTE, and
pathognomonic signs/symptoms ... is required for diagnosis ... : Serial negative ... in up to 30% of cases ... - Infectious Diseases