8 results
Pathophysiology of Diabetic Ketoacidosis (DKA) and Hyperglycemic Hyperosmolar Syndrome (HHS)
Absolute Insulin deficit:
 - Type I DM:
of Diabetic Ketoacidosis ... (DKA) and Hyperglycemic ... Polydipsia #dka ... #hhs #pathophysiology ... #comparison #endocrinology
DKA DIAGNOSTIC CRITERIA:
1. Serum glucose >250 mg/dL
2. Arterial pH <7.3
3. Serum bicarbonate <18 mEq/L
4. At least
Arterial pH <7.3 ... ketoacidosis (EDKA ... risk factor for EDKA ... presentation to EDKA ... Common, early signs
Pathogenesis and Pathophysiology of Diabetic Ketoacidosis (DKA)

DKA is a result of an absolute or relative insulin
of Diabetic Ketoacidosis ... (DKA) DKA is ... In DKA, the normal ... #Diabetic #Ketoacidosis ... #DKA #Diabetes
DKA vs HHS
 - Think of DKA and HHS on a spectrum of hyperglycemic emergencies
 -
DKA vs HHS - Think ... of DKA and HHS ... look like overlap DKA ... #comparison #diabetic ... #ketoacidosis #
Pathyophysiology - hyperglycemic crises in patients with diabetes 
Key signs/symptoms of HHS/DKA:
Both: Polyuria, polydipsia, weight loss,
Pathyophysiology ... Key signs/symptoms ... of HHS/DKA: Both ... , hypotension) DKA ... #IM #Endo #DKA
Hyperglycemic Crisis - Algorithm for DKA/HHS

Diagnostic criteria for DKA:
 • pH < 7.3
 • Anion gap
Algorithm for DKA ... criteria for DKA ... MatthewHoMD #DKA ... #Diabetes #DM2 ... #Ketoacidosis
Ketosis Disorders
Ketone bodies are a normal metabolic energy source. Excessive unregulated production of ketones, often accompanied
Diabetic ketoacidosis ... (DKA) - caused ... • Euglycemic DKA ... • DKA/HHS Overlap ... features of both DKA
Diabetic Ketoacidosis (DKA) - Pathogenesis and Clinical Findings
 • Note: in DKA, body K+ is lost
Diabetic Ketoacidosis ... (DKA) - Pathogenesis ... Findings • Note: in DKA ... Treating DKA: 1) ... Signs/Symptoms/Complications