6 results
Pathophysiology of Diabetic Ketoacidosis (DKA) and Hyperglycemic Hyperosmolar Syndrome (HHS)
Absolute Insulin deficit:
 - Type I DM:
Pathophysiology ... of Diabetic Ketoacidosis ... - Type II DM pts ... insulin demand Relative ... #comparison #endocrinology
Euglycemic Diabetic Ketoacidosis (EuDKA)
SGLT2 Inhibitors
Increasing Indications
Significant Adverse Drug Effects
Definition of EuDKA
 • Metabolic acidosis with pH
Euglycemic Diabetic ... acidosis with pH ... level < 200 mg/dL Pathophysiology ... #Diabetic #Ketoacidosis ... diagnosis #management #endocrinology
Ketosis Disorders
Ketone bodies are a normal metabolic energy source. Excessive unregulated production of ketones, often accompanied
• Alcoholic ketoacidosis ... • Diabetic ketoacidosis ... • Euglycemic ... of both DKA & HHS ... diagnosis #management #endocrinology
DKA DIAGNOSTIC CRITERIA:
1. Serum glucose >250 mg/dL
2. Arterial pH <7.3
3. Serum bicarbonate <18 mEq/L
4. At least
Arterial pH <7.3 ... admissions are Euglycemic ... Diabetic ketoacidosis ... Common, early signs ... closes and acidosis has
Diabetic Ketoacidosis (DKA) - Pathogenesis and Clinical Findings
 • Note: in DKA, body K+ is lost
Diabetic Ketoacidosis ... ensure patient has ... Signs/Symptoms/Complications ... DiabeticKetoacidosis #DKA #pathophysiology ... #endocrinology
Gangrenous cholecystitis with sloughed, intraluminal membranes on POCUS
Worsening RUQ pain/fever. Ill-appearing, low BP. WBC 22.4K. POCUS
POCUS GB done. ... Pt had stone stuck ... mucosal layer has ... US Murphy's sign ... is negative generally