30 results
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
40, F:M 9:1 • Clinical ... • Immunologic Workup ... pANCA anti-MPO - Negative ... • Evolution: Chronic ... disease Dr.
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Chronic Lymphocytic ... Orange or Hep C Clinical ... cells can indicate disease ... #diagnosis #workup ... #oncology #hematology
T-LGL leukemia - T-CeIl Large Granular Lymphocytic Leukemia
Clinical
 - Persistent (>6mo) lymphocytosis (2-20k) with proven clonality
Clinical - Persistent ... of autoimmune disease ... controversial - Negative ... version DDx: - chronic ... hemepath #pathology #diagnosis
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
Chronic Lymphocytic ... immunophenotype Clinical ... chemotherapy for low-risk disease ... #oncology #hematology ... #management
Gastrointestinal Evaluation of Iron Deficiency Anemia
In patients with anemia, diagnose iron deficiency if:
 • Ferritin <
inflammation or chronic ... Test for celiac disease ... endoscopy only if: • Negative ... change medical management ... Gastrointestinal #Evaluation #workup
Oroya Fever
Hematologic disease caused by Bartonella bacilliformis
Restricted to the Andes highlands of Peru & Ecuador
B. bacilliformis:
Oroya Fever Hematologic ... disease caused ... bacilliformis: - Gram negative ... Lutzomyia verrucarum Clinical ... #management #Bartonella
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines

ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic ... Failure (ACLF) Clinical ... underlying liver disease ... Failure #Cirrhosis #Hepatology ... #diagnosis
IgG4-Related Disease
Clinical history:  Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor
4 phenotypes:
 •
IgG4-Related Disease ... Clinical history ... • Some false negative ... #diagnosis #management ... #phenotypes #workup
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... pANCA anti-MPO - Negative ... • Evolution: Chronic ... disease Dr. ... #diagnosis #management
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
association • M > F Clinical ... Behcet syndrome (Clinical ... tears, Ischemia, Leukemia ... Recurrent and chronic ... #management #signs