10 results
Important Biostatistics and Epidemiology Equations

Sensitivity = TP / (TP + FN) = true positives / disease
) / Specificity ... Sensitivity vs ... Biostatistics #statistics ... #specificity #PPV ... #NPV
Sensitivity is the proportion of truly diseased persons in the screened population who are identified as
Specificity is the ... #Specificity #PositivePredictiveValue ... #NegativePredictiveValue ... Calculation #Table #PPV ... #Statistics #Matrix
Diagnostic algorithm for the workup of hypercalcemia. The diagnostic workup for patients presenting with hypercalcemia rests
Diagnostic algorithm ... value of 0.0115, sensitivity ... ) was 0.80 and specificity ... Thus, further testing ... #Differential #Algorithm
Commonly Used Diagnostic Tests for Celiac Disease

Tissue transglutaminase (tTG) IgA antibodies
 - Most reliable noninvasive test
test - High sensitivity ... and specificity ... and specificity ... Celiac #Disease #Testing ... Tests #Diagnosis #Workup
1,3-Beta-D-Glucan and Galactomannan Testing Sensitivity Specificity and False Positives
1,3-Beta-D-Glucan
 • Cell wall component of many fungi
Galactomannan Testing ... Sensitivity Specificity ... 96% • Higher specificity ... dx of IA PPV ... Galactomannan #Fungal #Testing
Diagnosis Adrenal Insufficiency - Algorithm

Step 1) Screening Test: 6-8AM Cortisol Level
 - Early morning cortisol levels
Insufficiency - Algorithm ... have almost 100% specificity ... for AI (but low sensitivity ... require Cosyntropin testing ... Insufficiency #Algorithm
This requires defining some general cutoff values for likelihood ratios.  These are admittedly arbitrary, but
boundaries to work ... relationship between sensitivity ... /specificity and ... #Diagnosis #Statistics ... #Sensitivity #Specificity
USMLE Epidemiology and Biostatistics Summary
Meta-Analysis: pools data from several studies (greater power), limited by quality/bias of
Sensitivity (rule ... Specificity (rule ... FN) Higher specificity ... Higher sensitivity ... probability of getting
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases

• Septic arthritis - Gram stain and culture of
Rheumatology Workup ... - CCP antibody testing ... has higher specificity ... test but lower sensitivity ... Arthritis #laboratory #workup
Celiac Disease - Diagnosis Algorithm
IgA TTG has high sensitivity and specificity of ~ 98% and is
Disease - Diagnosis Algorithm ... IgA TTG has high sensitivity ... and specificity ... pts need further testing ... gastroenterology #workup