4 results
Thrombocytopenia and Pregnancy
Three syndromes in the critically ill pregnant woman who presents with coagulation defects.
1) HELLP
require plasma exchange ... TTPHUS #HELLP #AFLP ... #Obstetrics #OBGyn ... #Hematology #Diagnosis ... #Comparison #Table
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
(DIC, ascites, jaundice ... infiltration) Differential ... Hepatitis, Preeclampsia ... #hepatology #obstetrics ... #obgyn #diagnosis
Liver Disease in Pregnancy
Intrahepatic Cholestasis of Pregnancy (ICP)
 • Onset/Trimester: 25-32 weeks
 • Typical clinical features:
Pruritus, Mild jaundice ... #hepatology #obstetrics ... #hepatitis #comparison ... #differential # ... diagnosis #icp #
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
hyperpigmentation • Jaundice ... bile ducts Differential ... Viral hepatitis, ... cholestasis of pregnancy ... #workup #hepatology