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antiarrhythmics cardiology pharmacology classification actionpotential agents class1 neurology neuron phases vaughan vaughanwilliams williams
Action Potential: Depolarization and repolarization of a neuron #ActionPotential #Depolarization #Repolarization #Neuron #Neurology #Pathophysiology
Action Potential ... : Depolarization ... ActionPotential #Depolarization ... #Repolarization ... #Pathophysiology
Class I Antiarrhythmics and their Key Pharmacologic Properties Class IA = Quinidine, Procainamide, Disopyramide ("Quarter PounDer") Class IB
Class I Antiarrhythmics ... for the rapid depolarization ... • Slows depolarization ... involved in phase 3 repolarization ... • Prolongs repolarization
Antiarrhythmics Pharmacology Summary Cardiac Conduction Phases: Phase 0 - Ventricular Depolarization: • Na+ channels open leading to a
- Ventricular Depolarization ... Classification: CLASS ... duration - CLASS ... duration - CLASS ... #pathophysiology
Antiarrhythmics - Vaughan Williams Classification: CLASS 1 - Sodium Channel Blockers: • MOA: Block fast Na+ channels
and magnitude of depolarization ... phase 4 to slow depolarization ... prolong AV node repolarization ... interval (delays time repolarization ... #pathophysiology
Antiarrhythmics - Vaughan Williams Classification Class I (Ia, Ib, Ic) - Na+ Channel Blockade • Slows depolarization
Classification Class ... Blockade • Slows depolarization ... Widens QRS complex Class ... Blockade • Slows depolarization ... Blockade • Slows depolarization
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