8 results
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations

 • Immune Complex Deposition
    - Arthralgia, Arthritis
80%) - Proximal Weakness ... • Myopathy (Also ... caused by hydroxychloroquine ... Complications #pathophysiology ... #signs #symptoms
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
lateral sclerosis Pathophysiology ... - Causes progressive ... weakness in the ... bulbar region, Weakness ... fasciculations Common Symptoms
Pott's Disease in Tuberculosis - Diagnosis and Management Summary
Epidemiology:
 - Typically from TB endemic areas
 -
extrapulmonary cases ... Clinical Signs/Symptoms ... - Assess for weakness ... decreased reflexes Pathophysiology ... should be done in ALL
Hypochloremia - Differential Diagnosis Algorithm

Cause - Decreased Intake:
 • Low salt in diet
 • Exclusive D5W
Differential Diagnosis Algorithm ... SIGNS: • Muscle weakness ... Hypotension • AMS ... Differential #Diagnosis #Algorithm ... #Pathophysiology
Scurvy (Vitamin C Deficiency) - Diagnosis and Management

Vitamin C is required for hydroxylation of proline residues
and tachypnea As ... Psychiatric symptoms ... • Myalgias • Weakness ... , or any other cause ... #VitaminC #AscorbicAcid
Guillain-Barré Syndrome (GBS)
Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness
Epidemiology:
 • Incidence: 1
progressive flaccid weakness ... Incidence: 1 to 2 cases ... symmetric muscle weakness ... than one after symptom ... the underlying pathophysiology
Evaluation and Management of Hypokalemia

Hypokalemia is often asymptomatic. Evaluation begins with a search for warning signs
warning signs or symptoms ... These include weakness ... Most cases of hypokalemia-induced ... hypomagnesemia are also ... Hypokalemia #Evaluation #Algorithm
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Evaluation of Recurrent Falls

Core Concept:
Maintaining an upright posture requires the integrated function of multiple systems.
Disruption in
presyncope, exertional symptoms ... Retinopathy • Clues ... Myopathies - Motor neuron ... disease (ALS) ... • Clues: Focal weakness