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diagnosis nephrology rheumatology syndrome activation algorithm cancer differential diuresis diuretics emergencies excretion macrophage mas medications oncologic pharmacology renal sjogrens sodium
Oncologic Emergencies - Differential Diagnosis Framework HEMATOLOGIC ONCOLOGIC EMERGENCIES: Hyperviscosity Syndrome: • Spontaneous bleeding • Shortness of breath
Diagnosis Framework HEMATOLOGIC ... • Early death Neutropenic ... possible coma SIADH ... : • Hyponatremia ... • Nausea, vomiting
Management of SIADH Treat underlying cause: • Causes can include pain, primary lung pathology, post-operative phenomenon, medications,
Management of SIADH ... : • Causes can ... SatyaPatelMD #SIADH ... #Management #hyponatremia ... #nephrology #treatment
Management of Hyponatremia Hypertonic Saline - Only indicated if patient has severe symptoms + Na < 125 Give
Management of Hyponatremia ... Normalizes in SIADH ... • IF SIADH — ... look for cause ... Wilkinsonjonny #Hyponatremia
SIADH Treatment Options 1. Treat underlying cause of SIADH: Pain, Primary lung pathology, Post-operative phenomenon, Medications, Basically
SIADH Treatment ... of SIADH: Pain, ... administered • This can cause ... #Management #hyponatremia ... #nephrology #treatment
Diuretics and Agents Regulating Renal Excretion Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide) • Glaucoma • Epilepsy • Altitude
irrigation • Management ... nephrotic syndrome • Hyponatremia ... Kidney stones caused ... Tolvaptan) • Treatment ... and euvolemic hyponatremia
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
erythematosus [SLE ... 10,000 ng/mL • Hyponatremia ... Treatment: • Corticosteroids ... Syndrome #Diagnosis #Management ... #Hematology #Rheumatology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
overlaps with RA, SLE ... Hypocomplementemia • Can cause ... DI Hematologic ... Adenocarcinoma Treatment ... #Diagnosis #Management
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