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diagnosis nephrology differential sodium cancer table workup chemotherapy diuresis diuretics electrolytes excretion hypotonic low medications oncology pharmacology physiologic renal uricacid
Hypernatremia Diagnosis and Workup Step 1 . Repeat the sodium concentration. Step 2. Check plasma osmolality. NORMAL PLASMA
Hypernatremia Diagnosis ... Workup Step 1 ... mmol/L - true hyponatremia ... EUVOLEMIC • SIADH ... renal failure #Hypernatremia
Hyponatremia Differential Diagnosis Algorithm - Utilizing Uric Acid ADH promotes Urea/uric acid excretion along with water
Hyponatremia Differential ... water retention 1) ... Low Uric Acid → SIADH ... Rachel Stern MD #Hyponatremia ... #nephrology #sodium
Cancer agents and Electrolyte Disorders • Hypocalcemia: Cisplatin from Low Mg, Cetuximab- due to low Mg Axitinib,
Cancer agents and ... Electrolyte Disorders ... Trastuzumab • Hyponatremia ... resistance, PD-1 ... #Cancer #agents
Hypernatremia - Differential Diagnosis Workup Algorithm 1) Check Urine Osmolality: > 600 mOsm/kg - Implies extrarenal mechanism
Hypernatremia - ... 1) Check Urine ... Extrarenal Hypernatremia ... Ingestion Renal Hypernatremia ... MatthewHoMD #Hypernatremia
Physiologic Approach to Hypotonic Hyponatremia The next time you have a case of hypotonic hyponatremia, give the
Approach to Hypotonic Hyponatremia ... case of hypotonic hyponatremia ... normal volume-based algorithm ... +K / serum Na >1 ... Physiologic #Hypotonic #Hyponatremia
Diuretics and Agents Regulating Renal Excretion Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide) • Glaucoma • Epilepsy • Altitude
Diuretics and Agents ... nephrotic syndrome • Hyponatremia ... specific bleeding disorders ... and euvolemic hyponatremia ... Excretion #Diuresis #Nephrology
Hyponatremia Differential Diagnosis Algorithm in Cancer UOsm ≥ 100 mOsm/kg = Urine is inappropriately concentrated for hypotonic
Hyponatremia Differential ... Diagnosis Algorithm ... inappropriate • SIAD ... adrenalitis; PD-1 ... metastases) #Hyponatremia
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