12 results
Acute Spinal Cord Injuries: Pathogenesis and clinical findings
 • Anterior Cord Syndrome -> Anterior spinal artery
Syndrome ->Cord ... bladder and rectal reflex ... pathophysiology #signs ... #symptoms #msk ... #orthopedics #neurology
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Disease 3 Types ... Agglutinin Syndrome ... Circulatory Symptoms ... symptoms - most ... hemolytic #anemia #hematology
Spinal Cord Disorders - Differential Diagnosis Framework

Spinal cord neurological lesion:
Clinical findings:
 • Symptoms and signs below
and signs below ... Sarcoidosis, Behcet disease ... MCTD, Sjogren syndrome ... dysfunction • Abnormal reflexes ... disorders #diagnosis #neurology
Alzheimer’s Disease: Pathogenesis and Clinical Findings
Risk factor for Late Onset Alzheimer's (99% of cases):
 - Increasing
Alzheimer’s Disease ... mutations - Down syndrome ... chromosome 21) Signs ... seizure, primitive reflexes ... #symptoms
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
skin injury) • Neurologic ... matter, spinal cord ... meningitis), MCC CNS symptoms ... diagnosis #management #signs ... #symptoms #rheumatology
Multiple Sclerosis - Summary

Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
neurodegenerative disease ... • Or brainstem syndromes ... Signs and symptoms ... Progressive MS (Spinal cord ... objective evidence of neurologic
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
Spasticity - Reflexes ... • Bilateral signs ... and/or symptoms ... MCTD - Bechet disease ... diagnosis #management #neurology
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
• Heavy Chain disease ... et diutinum Neurologic ... anemia due to cold ... Sneddon-Wilkinson disease ... Paraproteinemias #Hematology
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
Presentation: - Disease ... multiple spinal cord ... Increased Jaw Jerk reflex ... fasciculations Common Symptoms ... Lateral #Sclerosis #neurology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
• Cogan Syndrome ... Presentation - Systemic Symptoms ... purpura: strong sign ... • ANA (Suggest CTD ... differential #diagnosis #rheumatology