14 results
Drugs affecting the cardiac action potential. The sharp rise in voltage ("0") corresponds to the influx
the influx of sodium ... the two decays ("1" ... and "3", respectively ... the repolarizing eflux ... Pharmacology #Cardiology #Antiarrhythmics
Hypernatremia Differential Diagnosis Algorithm - Diabetes Insipidus Workup

Step #1 - Consider the history
Step #2 - Assess
Hypernatremia Differential ... Workup Step #1 ... Uglucose Step #3 ... Management #Algorithm #Sodium ... #nephrology #insipidus
Hypernatremia Diagnosis and Workup

Step 1 . Repeat the sodium concentration.
Step 2.  Check plasma osmolality.
NORMAL PLASMA
Hypernatremia Diagnosis ... Workup Step 1 ... Repeat the sodium ... administration Step 3. ... Workup #Algorithm #Nephrology
Cerebral Salt Wasting vs SIADH - Pathophysiology 
1) Neurological event
2) Sodium loss from tubules
3) Naturiesis →
Pathophysiology 1) ... Neurological event 2) Sodium ... from tubules 3) ... #hyponatremia # ... comparison
Hyponatremia Differential Diagnosis Algorithm - Utilizing Uric Acid 
ADH promotes Urea/uric acid excretion along with water
Hyponatremia Differential ... water retention 1) ... Urine Osmolarity 3) ... Urine Sodium 4) ... Diagnosis #Algorithm #nephrology
Hypernatremia - Differential Diagnosis and Treatment
Hypernatremia is almost always due to unreplaced water loss (free water
output is a clue). 1) ... post-obstructive 3) ... Diabetes Insipidus: neurogenic ... ([Na] / 140) - 1) ... #sodium
Hypernatremia - Differential Diagnosis Workup Algorithm

1) Check Urine Osmolality:
 > 600 mOsm/kg - Implies extrarenal mechanism
Hypernatremia - ... Workup Algorithm 1) ... insipidus (central or nephrogenic ... Workup #Algorithm #nephrology ... #sodium
Hyponatremia - Diagnosis and Treatment
Hyponatremia is usually caused by the inability to excrete water normally.
Then, ask 3 questions ... 1) Is it hypotonic ... 3) Is it appropriate ... Treatment #management #nephrology ... #sodium
Hyponatremia Diagnostic Algorithm
1) Check serum osmolality
2) Check urine osmolality
3) ADH Dependent - Check volume status, urine
Hyponatremia Diagnostic ... Algorithm 1) Check ... urine osmolality 3) ... status, urine sodium ... #nephrology
Antiarrhythmics Pharmacology Summary
Cardiac Conduction Phases:
Phase 0 - Ventricular Depolarization:
 • Na+ channels open leading to a
Antiarrhythmics ... ventricles to relax ... Classification: CLASS 1 ... - Sodium Channel ... @accpcardprn #Antiarrhythmics