9 results
Cerebral Salt Wasting vs SIADH - Pathophysiology 
1) Neurological event
2) Sodium loss from tubules
3) Naturiesis →
- Pathophysiology ... 1) Neurological ... event 2) Sodium ... #diagnosis #nephrology ... #hyponatremia #
Hyponatremia Differential Diagnosis Algorithm - Utilizing Uric Acid 
ADH promotes Urea/uric acid excretion along with water
Hyponatremia Differential ... water retention 1) ... Serum Osmolarity 2) ... Low Uric Acid → SIADH ... Diagnosis #Algorithm #nephrology
Hypernatremia Diagnosis and Workup

Step 1 . Repeat the sodium concentration.
Step 2.  Check plasma osmolality.
NORMAL PLASMA
Workup Step 1 ... Repeat the sodium ... Step 2. ... EUVOLEMIC • SIADH ... Workup #Algorithm #Nephrology
Hypernatremia - Differential Diagnosis Workup Algorithm

1) Check Urine Osmolality:
 > 600 mOsm/kg - Implies extrarenal mechanism
Workup Algorithm 1) ... renal mechanism 2) ... insipidus (central or nephrogenic ... Workup #Algorithm #nephrology ... #sodium
Hypernatremia - Differential Diagnosis and Treatment
Hypernatremia is almost always due to unreplaced water loss (free water
output is a clue). 1) ... water unavailable 2) ... Diabetes Insipidus: neurogenic ... ([Na] / 140) - 1) ... #sodium
SIADH Treatment Options
1. Treat underlying cause of SIADH: Pain, Primary lung pathology, Post-operative phenomenon, Medications, Basically
Options 1. ... Basically anything 2. ... purposes, restrict to 1 ... promoting passive sodium ... #Management #hyponatremia
Antiarrhythmics Pharmacology Summary
Cardiac Conduction Phases:
Phase 0 - Ventricular Depolarization:
 • Na+ channels open leading to a
Antiarrhythmics ... ventricles to relax ... Classification: CLASS 1 ... - Sodium Channel ... Classification #Classes #pathophysiology
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
2 cases/100,000 ... Guillain-Barre Pathophysiology ... Decreased / Absent Reflexes ... /constipation, hyponatremia ... management #treatment #neurology
Heat Illnesses and Heat Stroke - Differential Diagnosis Framework

Heat Cramps:
 • Muscle pain or spasm -
Dehydration - Loss of sodium ... conditions - Neurogenic ... heat illness → Hypernatremia ... Multi-system illness: 1. ... encephalopathy) 2.