21 results
Cerebral Salt Wasting vs SIADH - Pathophysiology 
1) Neurological event
2) Sodium loss from tubules
3) Naturiesis →
- Pathophysiology ... 1) Neurological ... event 2) Sodium ... #diagnosis #nephrology ... #hyponatremia #
Hyponatremia Differential Diagnosis Algorithm - Utilizing Uric Acid 
ADH promotes Urea/uric acid excretion along with water
Hyponatremia Differential ... water retention 1) ... Serum Osmolarity 2) ... Low Uric Acid → SIADH ... Diagnosis #Algorithm #nephrology
Hypernatremia Diagnosis and Workup

Step 1 . Repeat the sodium concentration.
Step 2.  Check plasma osmolality.
NORMAL PLASMA
Workup Step 1 ... Repeat the sodium ... Step 2. ... EUVOLEMIC • SIADH ... Workup #Algorithm #Nephrology
Drugs affecting the cardiac action potential. The sharp rise in voltage ("0") corresponds to the influx
the two decays ("1" ... the repolarizing eflux ... characteristic plateau ("2" ... Pharmacology #Cardiology #Antiarrhythmics ... #Classes #Effect
Hypernatremia - Differential Diagnosis Workup Algorithm

1) Check Urine Osmolality:
 > 600 mOsm/kg - Implies extrarenal mechanism
Workup Algorithm 1) ... renal mechanism 2) ... insipidus (central or nephrogenic ... Workup #Algorithm #nephrology ... #sodium
Physiologic Approach to Hypotonic Hyponatremia
The next time you have a case of hypotonic hyponatremia, give the
time you have a case ... +K / serum Na >1 ... restriction alone in SIADH ... , Renal Sodium loss ... #nephrology
Hypernatremia - Differential Diagnosis and Treatment
Hypernatremia is almost always due to unreplaced water loss (free water
output is a clue). 1) ... water unavailable 2) ... Diabetes Insipidus: neurogenic ... ([Na] / 140) - 1) ... #sodium
SIADH Treatment Options
1. Treat underlying cause of SIADH: Pain, Primary lung pathology, Post-operative phenomenon, Medications, Basically
Options 1. ... Treat underlying cause ... Basically anything 2. ... promoting passive sodium ... #Management #hyponatremia
Management of SIADH
Treat underlying cause:
 • Causes can include pain, primary lung pathology, post-operative phenomenon, medications,
Management of SIADH ... restriction: • Restrict 1 ... promoting passive sodium ... #Management #hyponatremia ... #nephrology #treatment
Hyponatremia - Diagnosis and Treatment
Hyponatremia is usually caused by the inability to excrete water normally.
is usually caused ... 1) Is it hypotonic ... 2) Is ADH elevated ... the underlying cause ... #sodium