8 results
Cerebral Salt Wasting vs SIADH - Pathophysiology 
1) Neurological event
2) Sodium loss from tubules
3) Naturiesis →
- Pathophysiology ... 1) Neurological ... event 2) Sodium ... #diagnosis #nephrology ... #hyponatremia #
Hyponatremia Differential Diagnosis Algorithm - Utilizing Uric Acid 
ADH promotes Urea/uric acid excretion along with water
Diagnosis Algorithm ... water retention 1) ... Serum Osmolarity 2) ... Low Uric Acid → SIADH ... #nephrology #sodium
Hypernatremia Diagnosis and Workup

Step 1 . Repeat the sodium concentration.
Step 2.  Check plasma osmolality.
NORMAL PLASMA
Workup Step 1 ... Repeat the sodium ... Step 2. ... EUVOLEMIC • SIADH ... Diagnosis #Workup #Algorithm
Hypernatremia - Differential Diagnosis Workup Algorithm

1) Check Urine Osmolality:
 > 600 mOsm/kg - Implies extrarenal mechanism
Diagnosis Workup Algorithm ... 1) Check Urine ... renal mechanism 2) ... insipidus (central or nephrogenic ... #nephrology #sodium
Physiologic Approach to Hypotonic Hyponatremia
The next time you have a case of hypotonic hyponatremia, give the
normal volume-based algorithm ... +K / serum Na >1 ... , Renal Sodium loss ... renal perfusion (Heart ... #nephrology
Heat Illnesses and Heat Stroke - Differential Diagnosis Framework

Heat Cramps:
 • Muscle pain or spasm -
Dehydration - Loss of sodium ... conditions - Neurogenic ... illness → Hypernatremia ... Multi-system illness: 1. ... encephalopathy) 2.
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
2 cases/100,000 ... Guillain-Barre Pathophysiology ... Decreased / Absent Reflexes ... /constipation, hyponatremia ... management #treatment #neurology
Hyponatremia Differential Diagnosis Algorithm in Cancer
UOsm ≥ 100 mOsm/kg = Urine is inappropriately concentrated for hypotonic
Hyponatremia Differential ... Diagnosis Algorithm ... CAR-T- and IL-2- ... inappropriate • SIAD ... adrenalitis; PD-1