11 results
Cerebral Salt Wasting vs SIADH - Pathophysiology 
1) Neurological event
2) Sodium loss from tubules
3) Naturiesis →
- Pathophysiology ... 1) Neurological ... event 2) Sodium ... #diagnosis #nephrology ... #hyponatremia #
Hyponatremia Differential Diagnosis Algorithm - Utilizing Uric Acid 
ADH promotes Urea/uric acid excretion along with water
Diagnosis Algorithm ... water retention 1) ... Serum Osmolarity 2) ... Low Uric Acid → SIADH ... #Algorithm #nephrology
Hypernatremia Diagnosis and Workup

Step 1 . Repeat the sodium concentration.
Step 2.  Check plasma osmolality.
NORMAL PLASMA
Hypernatremia Diagnosis ... Workup Step 1 ... Repeat the sodium ... Step 2. ... EUVOLEMIC • SIADH
Hypernatremia - Differential Diagnosis Workup Algorithm

1) Check Urine Osmolality:
 > 600 mOsm/kg - Implies extrarenal mechanism
Differential Diagnosis ... Workup Algorithm 1) ... renal mechanism 2) ... Workup #Algorithm #nephrology ... #sodium
Physiologic Approach to Hypotonic Hyponatremia
The next time you have a case of hypotonic hyponatremia, give the
+K / serum Na >1 ... , Renal Sodium loss ... renal perfusion (Heart ... #differential #diagnosis ... #nephrology
Hypernatremia - Differential Diagnosis and Treatment
Hypernatremia is almost always due to unreplaced water loss (free water
output is a clue). 1) ... , Dehydration: neurologic ... water unavailable 2) ... ([Na] / 140) - 1) ... #sodium
Heat Illnesses and Heat Stroke - Differential Diagnosis Framework

Heat Cramps:
 • Muscle pain or spasm -
Dehydration - Loss of sodium ... conditions - Neurogenic ... illness → Hypernatremia ... Multi-system illness: 1. ... encephalopathy) 2.
Noncardiogenic Pulmonary Edema - Differential Diagnosis Framework

NCPE Pathophysiology:
Noncardiogenic pulmonary edema occurs because of excessive pulmonary capillary
- Differential Diagnosis ... Framework NCPE Pathophysiology ... Causes include: 1. ... system activity, 2. ... /eclampsia • Neurogenic
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
2 cases/100,000 ... Guillain-Barre Pathophysiology ... Decreased / Absent Reflexes ... /constipation, hyponatremia ... management #treatment #neurology
Hyponatremia Differential Diagnosis Algorithm in Cancer
UOsm ≥ 100 mOsm/kg = Urine is inappropriately concentrated for hypotonic
Hyponatremia Differential ... Diagnosis Algorithm ... CAR-T- and IL-2- ... inappropriate • SIAD ... adrenalitis; PD-1