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nephrology diagnosis differential hyponatremia management treatment workup cancer cerebral comparison di hypotonic low pathophysiology physiologic saltwasting uricacid
Hypernatremia Differential Diagnosis Algorithm - Diabetes Insipidus Workup Step #1 - Consider the history Step #2 - Assess
Diagnosis Algorithm ... Workup Step #1 ... history Step #2 ... Uglucose Step #3 ... #Sodium #nephrology
Hyponatremia Differential Diagnosis Algorithm - Utilizing Uric Acid ADH promotes Urea/uric acid excretion along with water
water retention 1) ... Serum Osmolarity 2) ... Urine Osmolarity 3) ... Low Uric Acid → SIADH ... #nephrology #sodium
Hypernatremia Diagnosis and Workup Step 1 . Repeat the sodium concentration. Step 2. Check plasma osmolality. NORMAL PLASMA
Workup Step 1 ... Repeat the sodium ... Step 2. ... administration Step 3. ... EUVOLEMIC • SIADH
Hypernatremia - Differential Diagnosis Workup Algorithm 1) Check Urine Osmolality: > 600 mOsm/kg - Implies extrarenal mechanism
1) Check Urine ... renal mechanism 2) ... Euvolemic: Diabetes insipidus ... (central or nephrogenic ... #nephrology #sodium
Cerebral Salt Wasting vs SIADH - Pathophysiology 1) Neurological event 2) Sodium loss from tubules 3) Naturiesis →
Pathophysiology 1) ... Neurological event 2) ... Sodium loss from ... tubules 3) Naturiesis ... #hyponatremia #
Hypernatremia - Differential Diagnosis and Treatment Hypernatremia is almost always due to unreplaced water loss (free water
water unavailable 2) ... post-obstructive 3) ... Diabetes Insipidus ... : neurogenic, nephrogenic ... #sodium
Physiologic Approach to Hypotonic Hyponatremia The next time you have a case of hypotonic hyponatremia, give the
normal volume-based algorithm ... +K / serum Na >1 ... , Renal Sodium loss ... differential #diagnosis #table ... #sodium #nephrology
Hyponatremia Diagnostic Algorithm 1) Check serum osmolality 2) Check urine osmolality 3) ADH Dependent - Check volume status, urine
Algorithm 1) Check ... serum osmolality 2) ... urine osmolality 3) ... status, urine sodium ... #nephrology
SIADH Treatment Options 1. Treat underlying cause of SIADH: Pain, Primary lung pathology, Post-operative phenomenon, Medications, Basically
Options 1. ... Basically anything 2. ... hospitalization) 3. ... promoting passive sodium ... #Management #hyponatremia
Hyponatremia Differential Diagnosis Algorithm in Cancer UOsm ≥ 100 mOsm/kg = Urine is inappropriately concentrated for hypotonic
Diagnosis Algorithm ... CAR-T- and IL-2- ... inappropriate • SIAD ... adrenalitis; PD-1 ... #nephrology #oncology
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