7 results
Hypernatremia - Differential Diagnosis Workup Algorithm

1) Check Urine Osmolality:
 > 600 mOsm/kg - Implies extrarenal mechanism
• Euvolemic (Low ... • Hypovolemic: Diuretics ... osmotic (solute) diuresis ... , Cushing syndrome ... Algorithm #nephrology #sodium
Physiologic Approach to Hypotonic Hyponatremia
The next time you have a case of hypotonic hyponatremia, give the
time you have a case ... alone in SIADH RAAS ... can be high or low ... ) RAAS Active (or ... Cirrhosis, Nephrotic syndrome
Modified Hyponatremia Algorithm
Hypertonic Hyponatremia: Hyperglycemia, Mannitol, Urologic irrigants
Hypotonic Hyponatremia: 
 • ADH ON (UOsm > 100):
Cirrhosis, Nephrotic syndrome ... - RAAS OFF ... , Medications (diuretics ... Primary polydipsia, Low ... Algorithm #diagnosis #sodium
Here’s a review of the Renin-Angiotensin-Aldosterone system (RAAS)

This is a very common pathway that clinicians should
aldosterone which does a lot ... while retaining sodium ... , which causes increased ... potassium-sparing diuretic ... #Pharmacology #
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
Hyponatremia ... • Nephrogenic ... Kidney stones caused ... and euvolemic hyponatremia ... #Nephrology #Pharmacology
Hyponatremia (<135 mEq/L) is a common electrolyte abnormality caused by an excess of total body water
release of anti-diuretic ... stimulated in states of low ... activated in states of low ... activation of RAAS ... #RAAS #Hypovolemia
Hyponatremia - Differential Algorithm
Isotonic Hyponatremia: Hyperlipidemia, Hyperproteinemia, Recent TURP
Hypotonic Hyponatremia: 
 • Hypovolemia: Diuretics/Nephropathies, Vomiting, Diarrhea,
• Hypovolemia: Diuretics ... Cirrhosis, Nephrotic Syndrome ... Algorithm #diagnosis #causes ... #nephrology #sodium ... #low