9 results
Hypernatremia - Differential Diagnosis Workup Algorithm

1) Check Urine Osmolality:
 > 600 mOsm/kg - Implies extrarenal mechanism
Hypernatremia - ... Extrarenal Hypernatremia ... Ingestion Renal Hypernatremia ... MatthewHoMD #Hypernatremia ... Algorithm #nephrology #sodium
Hypernatremia Classification and Features According to Volume Status
 - Hypervolemic hypernatremia - Cushing's syndrome, Primary hyperaldosteronism,
Hypernatremia Classification ... - Hypervolemic hypernatremia ... - Cushing's syndrome ... - Normovolemic hypernatremia ... Features #Diagnosis #Comparison
Cerebral Salt Wasting vs SIADH - Pathophysiology 
1) Neurological event
2) Sodium loss from tubules
3) Naturiesis →
Wasting vs SIADH - Pathophysiology ... Neurological event 2) Sodium ... SaltWasting #SIADH #Pathophysiology ... diagnosis #nephrology #hyponatremia ... #comparison
Hyponatremia - Diagnosis and Treatment
Hyponatremia is usually caused by the inability to excrete water normally.
Hyponatremia - Diagnosis ... and Treatment Hyponatremia ... Treatment of hyponatremia ... demyelination syndrome ... of symptomatic (seizures
Hyponatremia (<135 mEq/L) is a common electrolyte abnormality caused by an excess of total body water
Hyponatremia (<135 ... body water in comparison ... urea causes the hyponatremia ... True hyponatremia ... #hyponatremia #ADH
Anticonvulsants as Mood Stabilizers: Mechanism and Side-effect
Examples: Valproate, Carbamazepine, Lamotrigine
 • Mild anticholinergic effect -> Drowsiness
Stevens-Johnson Syndrome ... -> Withdrawal seizure ... vomiting, diarrhea, hyponatremia ... #SideEffects #Pathophysiology
Heat Illnesses and Heat Stroke - Differential Diagnosis Framework

Heat Cramps:
 • Muscle pain or spasm -
Dehydration - Loss of sodium ... conditions - Neurogenic ... heat illness → Hypernatremia ... Collapse: • Pathophysiology ... consciousness, Coma/seizure
Gitelman Syndrome Overview

What?
• Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter
• Gitelman's syndrome
thiazide-sensitive sodium ... thiazide-sensitive sodium ... Renal tubular acidosis ... tachycardia • Seizures ... nephrology #management #pathophysiology
Bulimia Nervosa: Complications
GASTROINTESTINAL
 • Dehydration & inability to digest food -> Constipation
 • Recurrent vomiting exposes
• Boerhaave syndrome ... lead to metabolic acidosis ... hypochloremia, hypernatremia ... Complications #pathophysiology