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diagnosis algorithm causes hyponatremia lactate management table alkalosis chloride classification criticalcare defects elevation epithelial gitelman heat heatstroke hypokalemia hypotonic illness
Hypernatremia - Differential Diagnosis Workup Algorithm 1) Check Urine Osmolality: > 600 mOsm/kg - Implies extrarenal mechanism
Differential Diagnosis ... • Euvolemic (Low ... #Differential # ... Workup #Algorithm #nephrology ... #sodium
Lactic Acidosis - Differential Diagnosis Framework Type A: Impaired O2 Delivery (DO2) • Decreased O2 Delivery: Hypotension
Lactic Acidosis ... - Differential Diagnosis ... Hypothermia & Shivering, Seizures ... toxic alcohols, Sodium ... #Acidosis #Differential
Inherited Defects in Kidney Tubule Epithelial Cells Renal glucosuria - Na+-dependent glucose cotransporter Cystinuria - Amino acid transporter Bartter
cell epithelial sodium ... of epithelial sodium ... renal tubular acidosis ... Defects #Kidney #Nephrology ... #Diagnosis #Differential
Metabolic Alkalosis - Urinary Chloride Algorithm Cl- responsive metabolic alkalosis • Kidney loss of Cl-
alkalosis • Normal/low ... , Gitelman syndrome ... ketoacidosis • D-lactic ... urine #Algorithm #nephrology ... #differential #
Physiologic Approach to Hypotonic Hyponatremia The next time you have a case of hypotonic hyponatremia, give the
: SIADH, Renal Sodium ... can be high or low ... Cirrhosis, Nephrotic syndrome ... #differential # ... #nephrology
Hyponatremia - Diagnosis and Treatment Hyponatremia is usually caused by the inability to excrete water normally.
demyelination syndrome ... of symptomatic (seizures ... #Differential # ... Treatment #management #nephrology ... #sodium
Heat Illnesses and Heat Stroke - Differential Diagnosis Framework Heat Cramps: • Muscle pain or spasm -
Dehydration - Loss of sodium ... conditions - Neurogenic ... heat illness → Hypernatremia ... consciousness, Coma/seizure ... Possible DIC - Mild lactic
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis The most common causes of hyperlactatemia are usually:
Acidosis - Differential ... Heavy exercise - Seizures ... LV failure - Low ... - Compartment syndrome ... #Differential #
Hyponatremia - Differential Algorithm Isotonic Hyponatremia: Hyperlipidemia, Hyperproteinemia, Recent TURP Hypotonic Hyponatremia: • Hypovolemia: Diuretics/Nephropathies, Vomiting, Diarrhea,
Hyponatremia - Differential ... Cirrhosis, Nephrotic Syndrome ... #Differential # ... diagnosis #causes #nephrology ... #sodium #low
Gitelman Syndrome Overview What? • Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter • Gitelman's syndrome
alkalosis • Normal or low ... ratio 0.5%) Differential ... Renal tubular acidosis ... tachycardia • Seizures ... #diagnosis #nephrology
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