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diagnosis differential hyponatremia management causes rhabdomyolysis treatment algorithm gitelman hypotonic hypovolemia osmolality pathophysiology physiologic potomania raas siadh thiazides unaa
Modified Hyponatremia Algorithm Hypertonic Hyponatremia: Hyperglycemia, Mannitol, Urologic irrigants Hypotonic Hyponatremia: • ADH ON (UOsm > 100):
ON (UNa < 30): Hypovolemia ... Cirrhosis, Nephrotic syndrome ... Primary polydipsia, Low ... Algorithm #diagnosis #sodium ... #nephrology
Physiologic Approach to Hypotonic Hyponatremia The next time you have a case of hypotonic hyponatremia, give the
can be high or low ... Present (Uosm ≥100): Hypovolemia ... Cirrhosis, Nephrotic syndrome ... differential #diagnosis #table ... #sodium #nephrology
Hyponatremia (<135 mEq/L) is a common electrolyte abnormality caused by an excess of total body water
asymptomatic to seizures ... stimulated in states of low ... #hyponatremia #ADH ... #RAAS #Hypovolemia ... #EBV #potomania
Hyponatremia - Diagnosis and Treatment Hyponatremia is usually caused by the inability to excrete water normally.
volume status (EABV ... demyelination syndrome ... of symptomatic (seizures ... Treatment #management #nephrology ... #sodium
Gitelman Syndrome Overview What? • Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter • Gitelman's syndrome
thiazide-sensitive sodium ... alkalosis • Normal or low ... Renal tubular acidosis ... tachycardia • Seizures ... #diagnosis #nephrology
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary Causes of Rhabdomyolysis: • Trauma: - Immobilization - Crush injury - Compartment
exertion/training - Seizures ... Aldolase ↑ • LDH ... Hyperuricemia • Hyponatremia ... per day until stable ... causes #treatment #nephrology
Rhabdomyolysis - Differential Diagnosis Framework Rhabdomyolysis = Destruction of skeletal muscle with leakage of contents into circulation.
Strenuous exercise, Seizures ... Coxsackie virus, EBV ... Neuroleptic malignant syndrome ... Electrolytes: Hypokalemia ... #table
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