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diagnosis differential causes hyponatremia nephrology algorithm management ebv gitelman heat heatstroke hypotonic hypovolemia illness osmolality pathophysiology physiologic raas rhabdomyolysis siadh
Modified Hyponatremia Algorithm Hypertonic Hyponatremia: Hyperglycemia, Mannitol, Urologic irrigants Hypotonic Hyponatremia: • ADH ON (UOsm > 100):
ON (UNa < 30): Hypovolemia ... Cirrhosis, Nephrotic syndrome ... Primary polydipsia, Low ... solute intake, Beer potomania ... Algorithm #diagnosis #sodium
Physiologic Approach to Hypotonic Hyponatremia The next time you have a case of hypotonic hyponatremia, give the
can be high or low ... Present (Uosm ≥100): Hypovolemia ... Cirrhosis, Nephrotic syndrome ... solute intake (Beer potomania ... differential #diagnosis #table
Hyponatremia - Differential Diagnosis by Mechanism Decr Blood Pressure (“Decr Effective Circulating Volume”) - Volume depletion
Hyponatremia - Differential ... - Cirrhosis Syndrome ... polydipsia - Beer potomania ... Differential #Diagnosis #Table ... #Causes #Sodium
Etiologies of Hypernatremia - Differential Diagnosis GI losses / Insensible losses Sodium Overload Transcellular Movement of Water Central Diabetes Insipidus
Etiologies of Hypernatremia ... Insensible losses Sodium ... Insipidus (Decr ADH ... hypercalcemia - Chronic hypokalemia ... Differential #Diagnosis #Table
Hyponatremia (<135 mEq/L) is a common electrolyte abnormality caused by an excess of total body water
asymptomatic to seizures ... stimulated in states of low ... #hyponatremia #ADH ... #RAAS #Hypovolemia ... #EBV #potomania
Hyponatremia - Differential Algorithm Isotonic Hyponatremia: Hyperlipidemia, Hyperproteinemia, Recent TURP Hypotonic Hyponatremia: • Hypovolemia: Diuretics/Nephropathies, Vomiting, Diarrhea,
: • Hypovolemia ... Euvolemia: SIADH, Beer Potomania ... Cirrhosis, Nephrotic Syndrome ... causes #nephrology #sodium ... #low
Gitelman Syndrome Overview What? • Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter • Gitelman's syndrome
thiazide-sensitive sodium ... thiazide-sensitive sodium ... alkalosis • Normal or low ... Renal tubular acidosis ... tachycardia • Seizures
Heat Illnesses and Heat Stroke - Differential Diagnosis Framework Heat Cramps: • Muscle pain or spasm -
Dehydration - Loss of sodium ... conditions - Neurogenic ... heat illness → Hypernatremia ... consciousness, Coma/seizure ... - Hyperkalemia
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary Causes of Rhabdomyolysis: • Trauma: - Immobilization - Crush injury - Compartment
- Compartment syndrome ... exertion/training - Seizures ... Aldolase ↑ • LDH ... Hyperuricemia • Hyponatremia ... per day until stable
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