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diagnosis nephrology adh differential ebv epithelial hypokalemia hyponatremia hypovolemia inherited kidney management osmolality pathophysiology potomania raas siadh thiazides tubule unaa
Inherited Defects in Kidney Tubule Epithelial Cells Renal glucosuria - Na+-dependent glucose cotransporter Cystinuria - Amino acid transporter Bartter
Inherited Defects ... ascending limb Gitelman ... of epithelial sodium ... renal tubular acidosis ... #Differential #Table
Gitelman Syndrome Overview What? • Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter • Gitelman's syndrome
Gitelman Syndrome ... thiazide-sensitive sodium ... alkalosis • Normal or low ... Renal tubular acidosis ... tachycardia • Seizures
Hyponatremia (<135 mEq/L) is a common electrolyte abnormality caused by an excess of total body water
body water in comparison ... asymptomatic to seizures ... the hypothalamus detect ... stimulated in states of low ... activated in states of low
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