17 results
Hypernatremia - Differential Diagnosis Workup Algorithm

1) Check Urine Osmolality:
 > 600 mOsm/kg - Implies extrarenal mechanism
• Euvolemic (Low ... insipidus (central or nephrogenic ... Hypervolemic: Conn syndrome ... , Cushing syndrome ... Algorithm #nephrology #sodium
Hyponatremia - Diagnosis and Treatment
Hyponatremia is usually caused by the inability to excrete water normally.
is usually caused ... the underlying cause ... demyelination syndrome ... of symptomatic (seizures ... management #nephrology #sodium
Hyponatremia (<135 mEq/L) is a common electrolyte abnormality caused by an excess of total body water
electrolyte abnormality caused ... among the possible causes ... asymptomatic to seizures ... stimulated in states of low ... activated in states of low
Physiologic Approach to Hypotonic Hyponatremia
The next time you have a case of hypotonic hyponatremia, give the
time you have a case ... : SIADH, Renal Sodium ... can be high or low ... Cirrhosis, Nephrotic syndrome ... Primary polydipsia), Low
Anticonvulsants as Mood Stabilizers: Mechanism and Side-effect
Examples: Valproate, Carbamazepine, Lamotrigine
 • Mild anticholinergic effect -> Drowsiness
Stevens-Johnson Syndrome ... -> Withdrawal seizure ... Systemic effect -> Nausea ... vomiting, diarrhea, hyponatremia ... #SideEffects #Pathophysiology
Refeeding Syndrome Overview

What Is It?
	• Electrolyte/fluid shifts caused by initiation of nutrition in severely malnourished patient.
Electrolyte/fluid shifts caused ... changes and may cause ... Rhabdomyolysis • Seizures ... , K, Mg2+) • Slow ... Differential #Diagnosis #Pathophysiology
Heat Illnesses and Heat Stroke - Differential Diagnosis Framework

Heat Cramps:
 • Muscle pain or spasm -
Dehydration - Loss of sodium ... conditions - Neurogenic ... heat illness → Hypernatremia ... Collapse: • Pathophysiology ... consciousness, Coma/seizure
Digoxin Pharmacology and Pathophysiology
1) Na/K ATPase Pump - Digoxin works by directly binding to and inhibiting
Pharmacology and Pathophysiology ... intracellular calcium causes ... hypokalemia (or low ... #Pharmacology #Pathophysiology ... #cardiology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... high WBC count cause ... : • Pathophysiology ... dysrhythmias, seizures ... , Elevated Cr, Low
Noncardiogenic Pulmonary Edema - Differential Diagnosis Framework

NCPE Pathophysiology:
Noncardiogenic pulmonary edema occurs because of excessive pulmonary capillary
Framework NCPE Pathophysiology ... Causes include: ... respiratory distress syndrome ... /eclampsia • Neurogenic ... cerebral hemorrhage, seizure