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diagnosis nephrology causes classification management algorithm defects elevation epithelial gitelman heat heatstroke high hyperkalemia hypokalemia hyponatremia hypotonic illness inherited kidney
Hypernatremia - Differential Diagnosis Workup Algorithm 1) Check Urine Osmolality: > 600 mOsm/kg - Implies extrarenal mechanism
Differential Diagnosis ... • Euvolemic (Low ... , Cushing syndrome ... #Differential # ... Algorithm #nephrology #sodium
Inherited Defects in Kidney Tubule Epithelial Cells Renal glucosuria - Na+-dependent glucose cotransporter Cystinuria - Amino acid transporter Bartter
cell epithelial sodium ... of epithelial sodium ... renal tubular acidosis ... Nephrology #Diagnosis #Differential ... #Table
Physiologic Approach to Hypotonic Hyponatremia The next time you have a case of hypotonic hyponatremia, give the
: SIADH, Renal Sodium ... can be high or low ... Cirrhosis, Nephrotic syndrome ... #differential # ... diagnosis #table
Heat Illnesses and Heat Stroke - Differential Diagnosis Framework Heat Cramps: • Muscle pain or spasm -
Heat Stroke - Differential ... Dehydration - Loss of sodium ... conditions - Neurogenic ... heat illness → Hypernatremia ... consciousness, Coma/seizure
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary Causes of Rhabdomyolysis: • Trauma: - Immobilization - Crush injury - Compartment
Rhabdomyolysis - Differential ... exertion/training - Seizures ... Hyperuricemia • Hyponatremia ... per day until stable ... Rhabdomyolysis #Differential
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis The most common causes of hyperlactatemia are usually:
- Differential ... liver or renal injury ... LV failure - Low ... - Compartment syndrome ... #Elevation #Differential
Gitelman Syndrome Overview What? • Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter • Gitelman's syndrome
thiazide-sensitive sodium ... alkalosis • Normal or low ... ratio 0.5%) Differential ... Renal tubular acidosis ... tachycardia • Seizures
Causes of Hyperkalemia l. Pseudohyperkalemia A Cellular efflux; thrombocytosis, erythrocytosis, leukocytosis, in vitro hemolysis B.
Acidosis B. ... neuromuscular injury ... Drug-associated: heparin, low-molecular-weight ... antiphospholipid syndrome ... #Hyperkalemia #Differential
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