35 results
Causes of Hypernatremia - Differential Diagnosis
Inadequate water intake:
 • Lack of access to water
Extrarenal hypotonic fluid
Causes of Hypernatremia ... insipidus • Nephrogenic ... administration #Hypernatremia ... Differential #Diagnosis #Causes ... #nephrology #sodium
Generalized Seizures and Pseudoseizures
Generalized seizures "are conceptualized as originating as some point within, and rapidly engaging,
caused by a toxic ... and metabolic causes ... hyperglycemia, hyponatremia ... Classification #Diagnosis #Neurology ... #Signs #Symptoms
Hypernatremia - Differential Diagnosis Workup Algorithm

1) Check Urine Osmolality:
 > 600 mOsm/kg - Implies extrarenal mechanism
insipidus (central or nephrogenic ... Hypervolemic: Conn syndrome ... , Cushing syndrome ... Workup #Algorithm #nephrology ... #sodium
Causes of Seizures - Differential Diagnosis Algorithm
Unprovoked - Epilepsy:
 • Focal: Simple, Complex
 • Generalized: Absence,
Causes of Seizures ... vasoconstriction syndrome ... Hyperglycemia, Hyponatremia ... Diagnosis #Algorithm #Causes ... #neurology
Hyponatremia - Diagnosis and Treatment
Hyponatremia is usually caused by the inability to excrete water normally.
is usually caused ... demyelination syndrome ... of symptomatic (seizures ... Treatment #management #nephrology ... #sodium
Hyponatremia - Differential Diagnosis Algorithm
Hypovolemic - Give volume
Hypervolemic (Edematous) - Look for and treat underlying cause
Hyponatremia - Differential ... treat underlying cause ... cirrhosis, nephrotic syndrome ... Algorithm #diagnosis #nephrology ... #sodium
Hyponatremia Correction
1. Indications for Hypertonic Saline: seizure, coma, focal findings
   - typically occurs with
Hyponatremia Correction ... Hypertonic Saline: seizure ... 100-110 - Symptoms ... Demyelination Syndrome ... rate #management #nephrology
Anticonvulsants as Mood Stabilizers: Mechanism and Side-effect
Examples: Valproate, Carbamazepine, Lamotrigine
 • Mild anticholinergic effect -> Drowsiness
Stevens-Johnson Syndrome ... -> Withdrawal seizure ... , asthenia • Neurologic ... vomiting, diarrhea, hyponatremia ... #SideEffects #Pathophysiology
Physiologic Approach to Hypotonic Hyponatremia
The next time you have a case of hypotonic hyponatremia, give the
time you have a case ... : SIADH, Renal Sodium ... Cirrhosis, Nephrotic syndrome ... diagnosis #table #sodium ... #nephrology
Alzheimer’s Disease: Pathogenesis and Clinical Findings
Risk factor for Late Onset Alzheimer's (99% of cases):
 - Increasing
mutations - Down syndrome ... chromosome 21) Signs / Symptoms ... dysfunction: myoclonic seizure ... AlzheimersDisease #Dementia #pathophysiology ... diagnosis #signs #symptoms