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diagnosis differential causes nephrology classification epithelial gitelman heat heatstroke high hyperkalemia hypokalemia illness inherited kidney management pathophysiology potassium renal rta
Inherited Defects in Kidney Tubule Epithelial Cells Renal glucosuria - Na+-dependent glucose cotransporter Cystinuria - Amino acid transporter Bartter
Inherited Defects ... cotransporter in distal ... cell epithelial sodium ... of epithelial sodium ... renal tubular acidosis
Distal Renal Tubular Acidosis Distal RTA is the true Nephrogenic RTA and can be truly divided into
Distal Renal Tubular ... Acidosis Distal ... RTA is the true Nephrogenic ... diseases(Sjogren's Syndrome ... Renal #Tubular #Acidosis
Heat Illnesses and Heat Stroke - Differential Diagnosis Framework Heat Cramps: • Muscle pain or spasm -
Dehydration - Loss of sodium ... conditions - Neurogenic ... heat illness → Hypernatremia ... - Metabolic acidosis ... consciousness, Coma/seizure
Gitelman Syndrome Overview What? • Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter • Gitelman's syndrome
thiazide-sensitive sodium ... thiazide-sensitive sodium ... of cells on the distal ... Renal tubular acidosis ... tachycardia • Seizures
Causes of Hyperkalemia l. Pseudohyperkalemia A Cellular efflux; thrombocytosis, erythrocytosis, leukocytosis, in vitro hemolysis B.
Hereditary defects ... Acidosis B. ... the epithelial sodium ... Decreased distal ... antiphospholipid syndrome
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