8 results
Hypernatremia - Differential Diagnosis Workup Algorithm

1) Check Urine Osmolality:
 > 600 mOsm/kg - Implies extrarenal mechanism
Differential Diagnosis Workup ... Hypervolemic: Conn syndrome ... , Cushing syndrome ... #Algorithm #nephrology ... #sodium
Hypernatremia Diagnosis and Workup

Step 1 . Repeat the sodium concentration.
Step 2.  Check plasma osmolality.
NORMAL PLASMA
and Workup Step ... Repeat the sodium ... • nephrotic syndrome ... #Diagnosis #Workup ... #Algorithm #Nephrology
Inherited Defects in Kidney Tubule Epithelial Cells

Renal glucosuria - Na+-dependent glucose cotransporter
Cystinuria - Amino acid transporter
Bartter
cell epithelial sodium ... of epithelial sodium ... renal tubular acidosis ... -2 deficiency Nephrogenic ... Defects #Kidney #Nephrology
Heat Illnesses and Heat Stroke - Differential Diagnosis Framework

Heat Cramps:
 • Muscle pain or spasm -
Dehydration - Loss of sodium ... conditions - Neurogenic ... → Hypernatremia ... - Metabolic acidosis ... consciousness, Coma/seizure
Hyponatremia - Diagnosis and Treatment
Hyponatremia is usually caused by the inability to excrete water normally.
3 questions to work ... demyelination syndrome ... of symptomatic (seizures ... Treatment #management #nephrology ... #sodium
Lactic Acidosis - Differential Diagnosis Framework

Type A: Impaired O2 Delivery (DO2)
 • Decreased O2 Delivery: Hypotension
Ischemia, Compartment Syndrome ... Hypothermia & Shivering, Seizures ... Beta-Agonists, ↑ work ... toxic alcohols, Sodium ... in Short Bowel Syndrome
Stiff Person Syndrome (SPS) - Diagnosis and Management Summary

Epidemiology:
 • Prevalence: 1-2 cases per million -
Stiff Person Syndrome ... antibody that works ... Psychosomatic illness ... others (botox, sodium ... Management #treatment #neurology
Gitelman Syndrome Overview

What?
• Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter
• Gitelman's syndrome
thiazide-sensitive sodium ... thiazide-sensitive sodium ... Renal tubular acidosis ... tachycardia • Seizures ... #diagnosis #nephrology