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diagnosis nephrology differential management algorithm causes acidosis criticalcare diuresis diuretics excretion gitelman heat heatstroke hypokalemia hyponatremia illness lactate lactic medications
Hypernatremia - Differential Diagnosis Workup Algorithm 1) Check Urine Osmolality: > 600 mOsm/kg - Implies extrarenal mechanism
Differential Diagnosis Workup ... insipidus (central or nephrogenic ... Hypervolemic: Conn syndrome ... , Cushing syndrome ... Algorithm #nephrology #sodium
Hypernatremia Diagnosis and Workup Step 1 . Repeat the sodium concentration. Step 2. Check plasma osmolality. NORMAL PLASMA
Hypernatremia Diagnosis ... and Workup Step ... Repeat the sodium ... • nephrotic syndrome ... #Diagnosis #Workup
Hypernatremia - Differential Diagnosis and Treatment Hypernatremia is almost always due to unreplaced water loss (free water
Hypernatremia - ... Hypernatremia ... Diabetes Insipidus: neurogenic ... , nephrogenic 4 ... management #nephrology #sodium
Hyponatremia - Diagnosis and Treatment Hyponatremia is usually caused by the inability to excrete water normally.
3 questions to work ... Treatment: Treatment ... demyelination syndrome ... of symptomatic (seizures ... management #nephrology #sodium
Diuretics and Agents Regulating Renal Excretion Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide) • Glaucoma • Epilepsy • Altitude
disequilibrium syndrome ... • Hyponatremia ... • Nephrogenic ... Tolvaptan) • Treatment ... and euvolemic hyponatremia
Heat Illnesses and Heat Stroke - Differential Diagnosis Framework Heat Cramps: • Muscle pain or spasm -
Dehydration - Loss of sodium ... conditions - Neurogenic ... heat illness → Hypernatremia ... consciousness, Coma/seizure
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary Causes of Rhabdomyolysis: • Trauma: - Immobilization - Crush injury - Compartment
- Compartment syndrome ... exertion/training - Seizures ... Hyperuricemia • Hyponatremia ... or compartment syndrome ... Treatment of underlying
Lactic Acidosis - Differential Diagnosis Framework Type A: Impaired O2 Delivery (DO2) • Decreased O2 Delivery: Hypotension
Ischemia, Compartment Syndrome ... Hypothermia & Shivering, Seizures ... Beta-Agonists, ↑ work ... toxic alcohols, Sodium ... in Short Bowel Syndrome
Stiff Person Syndrome (SPS) - Diagnosis and Management Summary Epidemiology: • Prevalence: 1-2 cases per million -
Stiff Person Syndrome ... antibody that works ... Treatment: • ... others (botox, sodium ... Diagnosis #Management #treatment
Gitelman Syndrome Overview What? • Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter • Gitelman's syndrome
Gitelman Syndrome ... thiazide-sensitive sodium ... thiazide-sensitive sodium ... tachycardia • Seizures ... Rhabdomyolysis Treatment
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