11 results
Plantar Reflex on Newborn Physical Exam 
The normal response to stroking the lateral aspect of the
Plantar Reflex on ... Newborn Physical ... extension of the great toe ... toes or “Babinski sign ... #clinical #video
Retinoblastoma: Pathogenesis and clinical findings
 • Sporadic mutation -> One allele of RB1 tumor suppressor gene
Retinoblastoma Signs ... / Symptoms / Complications ... partial retinal red reflex ... Retinoblastoma #pathophysiology ... #symptoms
Primitive Suck, Rooting Reflex on Newborn Physical Exam 
The normal response to stroking the lateral aspect
on Newborn Physical ... aspect of the plantar ... extension of the great toe ... toes or “Babinski sign ... #clinical #video
Alzheimer’s Disease: Pathogenesis and Clinical Findings
Risk factor for Late Onset Alzheimer's (99% of cases):
 - Increasing
mutations - Down syndrome ... / Symptoms / Complications ... seizure, primitive reflexes ... AlzheimersDisease #Dementia #pathophysiology ... #symptoms
Prader-Willi Syndrome: Pathogenesis and clinical findings
 • Maternal uniparental disomy: inheriting 2 copies of maternal chromosome
Prader-Willi Syndrome ... Signs/Symptoms ... /Complications: ... Infertility • Decr Bone ... #genetics #pathophysiology
Cauda Equina Syndrome
Causes:
 • Large lumbar degenerative disc herniation (central)
 • Severe lumbar spondylosis
 • Neoplasm
Cauda Equina Syndrome ... / Symptoms / Complications ... of normal leg reflexes ... #MSK #pathophysiology ... #signs
Keratoconus: Pathogenesis and Clinical Findings
Genetics
 • Family history of keratoconus
 • Ehlers-Danlos syndrome
 • Down, Turner,
Ehlers-Danlos syndrome ... Turner, Marfan syndromes ... degeneration, and cone-shaped ... / Symptoms / Complications ... #Keratoconus #pathophysiology
The Neurological Evaluation of a Comatose Patient

Definition:
 • Coma: a state of unresponsiveness; the absence of
• Locked-in syndrome ... • Mutism Pathophysiology ... Motor/Sensory: • Tone ... • Plantar responses ... • Examine for signs
Spinal Cord Disorders - Differential Diagnosis Framework

Spinal cord neurological lesion:
Clinical findings:
 • Symptoms and signs below
and signs below ... spasticity - Extensor plantar ... decreased muscle tone ... MCTD, Sjogren syndrome ... dysfunction • Abnormal reflexes
Anorexia Nervosa: Complications
CARDIAC ABNORMALITIES
 - Functional: Low BP, Sinus bradycardia, prolonged QT interval
 - Structural: Reduced
Anorexia Nervosa: Complications ... mortality rates of all psychiatric ... #pathophysiology ... #diagnosis #signs ... #symptoms #psychiatry