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diagnosis management clinical differential hematology algorithm gastroenterology causes pathophysiology treatment pharmacology endoscopy pocus pulmonary video table criticalcare ultrasound classification comparison
Thresholds for Transfusion of Platelets in Adults Major surgery or invasive procedure, no active bleeding - ≤
Transfusion of Platelets ... procedure, no active bleeding ... Surgery with active bleeding ... < 10 Stable, nonbleeding ... #Management #Platelets
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 Indications for Transfusion Packed RBCs • Hgb <7 g/dL or hematocrit <21% in a patient with uncompromised
• < 30,000 and bleeding ... postoperative bleeding ... < 100,000 and bleeding ... Platelet transfusions ... • Prophylaxis (nonbleeding
Indications for Transfusion of Platelets in Neonates #Management #Peds #Pediatrics #Platelets #Transfusion #Plateletpheresis #Thresholds #NonBleeding #Surgery
Transfusion of Platelets ... Peds #Pediatrics #Platelets ... Plateletpheresis #Thresholds #NonBleeding
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 Idiopathic Thrombocytopenic Purpura Clinical: • Gingival • Menorrhagia • GI bleeding • Intracranial
Menorrhagia • GI bleeding ... children) • Platelets ... only for severe bleeding ... extremely low platelet
Inherited Qualitative Platelet Defects Bernard-Soulier Syndrome • Defect of adhesion due to a lack of GP Ib/IX/V
Inherited Qualitative Platelet ... Single isolated platelets ... without platelet ... failure Grey Platelet ... • Absence of platelet
Bleeding and Bruising - Differential Diagnosis Algorithm • Vascular System Defect - Congenital vs Acquired •
Bleeding and Bruising ... vs Acquired • Platelet ... vs Acquired #Bleeding
Platelet disorders and Aggregometry Glanzmann Thrombasthenia • Defective aggregation to all agonists except ristocetin • Normal platelet,
Platelet disorders ... ristocetin • Normal platelet ... count and platelet ... • Platelet flow ... Usually normal platelet
Thrombocytosis - Differential Diagnosis Platelet Count > 450 Reactive: • Anemia/blood loss (Fe deficiency) • Infection/Sepsis • Non-infectious
Differential Diagnosis Platelet ... Diagnosis #causes #Platelets
Blood Product Components, Contents, Volume and Shelf Life Whole blood (autologous or directed donations) - RBC and
WBC and platelets ... Hct 60% Platelet ... concentrate - Platelets ... Hct < .005) Platelet ... pheresis - Platelets
Forrest Classification for Peptic Ulcer Bleeding Rebleeding risks are without endoscopic intervention 1a - Spurting Bleed - 60-100%
Bleed - 60-100% Re-bleeding ... Bleed - 50% Re-bleeding ... IIa - Non-Bleeding ... Clot - 20-30% Re-bleeding ... Peptic #Ulcer #Bleeding
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