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diagnosis differential causes erythematosus extravascular hemolysis hemolytic intravascular lupus macrocytic microcytic oncology plasmacytoma polycythemia rheumatology sle solitary systemic testing
Anemia Diagnostic Algorithm Mean corpuscular (cell) volume (MCV): Average RBC size. Under 80 = microcytic. Between 80-95
Anemia Diagnostic ... corpuscular (cell ... Red cell distribution ... Normal range 11.5% ... #Workup #Hematology
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... • Sickle cells ... Consider sickle cell ... mechanical cardiac valve ... #workup #hematology
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
Differential Diagnosis Algorithm ... • Sickle cell ... immune-complex hemolytic anemia ... Prosthetic heart valves ... #Causes #Hematology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Angioimmunoblastic T-cell ... Cytopenias • Cardiac valve ... lymphopenia, low PLT • Anemia ... , Serositis Labs ... : • Chronic B-cell
Polycythemia - Differential Diagnosis Algorithm Polycythemia itself isn’t a diagnosis. Like many things, it is a condition
that a one-off value ... Too many cells in ... Better call hematology ... exogenous, EPO levels: normal ... #workup #hematology
Solitary Cell Plasmacytoma What? • Plasma cell neoplasms can present as a single lesion (solitary plasmacytoma) • In 3%
-70 y/o • 2/3 Males ... mainly in the oral ... • No CRAB - no anemia ... Oncology #Diagnosis #Workup ... #Hematology
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