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diagnosis differential injury rheumatology aclf aih alcoholic aplastic autoimmune causes chemistry chronic cirrhosis common cvid druginduced erythematosus failure gap gastroenterology
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines ACLF = possibly reversible condition in those with CLD (± cirrhosis)
disease, liver ... Alcohol-Associated Hepatitis ... Injury (DILI) ... Viral Hepatitis ... Failure #Cirrhosis #Hepatology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
disease, Hepatic ... dechallenge • Acute ... ascites), Chronic hepatitis ... • Autoimmune hepatitis ... #hepatology
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Acute Liver Injury ... Autoimmune: Autoimmune hepatitis ... Chronic viral hepatitis ... #injury #hepatitis ... #hepatology
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
viral hepatitis ... viral hepatitis ... Chronic viral hepatitis ... • Gilbert's syndrome ... #differential #Hepatology
Portal Hypertension - Differential Diagnosis Portal Pressure = the pressure difference between the pressure in the portal
and hepatorenal syndrome ... Clues to non-cirrhotic ... • Cirrhosis/acute ... hepatitis • Infiltrative ... Diagnosis #causes #hepatology
Autoimmune Hepatitis Clinical Presentation - Highly variable clinical presentation, from subclinical disease to acute liver failure. -
Autoimmune Hepatitis ... to acute liver ... Other Etiology of Hepatitis ... #Autoimmune #Hepatitis ... #Hepatology
Alcoholic Hepatitis - Management Algorithm Assess Eligibility for Treatment: - Maddrey Discriminant Function ≥ (or possibly MELD
Alcoholic Hepatitis ... - Management Algorithm ... #Alcoholic #Hepatitis ... #Management #Algorithm ... #hepatology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
: - Hepatitis ... ) Labs: • Peripheral ... Treatment: ... #oncology #hematology ... #diagnosis #management
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
• Liver diseases ... and hepatitis ... autoimmune hemolytic anemia ... levels are within normal ... hypogammaglobulinemia #immunology #hematology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Classification: • Acute ... Noninfectious hepatitis ... Cytopenias • Cardiac valve ... lymphopenia, low PLT • Anemia ... , Serositis Labs
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