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differential dermatology gap globulin hypogammaglobulinemia immunodeficiency management nonpalpable palpable pathophysiology proteingap purpura thrombosis variable vascular venous
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework VENOUS THROMBOSIS • Acquired Risk Factors: - >48 hours
Myeloproliferative disease ... • Nephrotic Syndrome ... , Ischemic Liver ... Arterial Embolism ... pathophysiology #hematology
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
• Liver diseases ... and hepatitis ... levels are within normal ... DDX - Other causes ... #hematology #diagnosis
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
- Hemolytic anemia ... deficiency • Liver ... Retiform purpura - Protein ... Associated - SLE, Sjogren's ... #hematology #rheumatology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
hepatitis C) • ... ETOH, autoimmune hepatitis ... PBC, PSC, Viral hepatitis ... gastric tumors • Hematology ... #hematology
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