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algorithm hepatitis hodgkins lfts lymphoma obstetrics pregnancy anemia aplastic apml biliary chemistry cholangitis cirrhosis classification differentiation disease enzymes fatty hellp
Liver Disease in Pregnancy Intrahepatic Cholestasis of Pregnancy (ICP) • Onset/Trimester: 25-32 weeks • Typical clinical features:
Hepatic imaging: Normal ... • Histology: Normal-mild ... Disease #Pregnancy #hepatology ... #differential # ... diagnosis #icp #
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Interpretation of LFTs R-value ... - If both are normal ... • Near normal ... #differential # ... Hepatology #transaminitis
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
of Pregnancy (AFLP ... Antithrombin Ill • Ultrasound ... infiltration) Differential ... Diagnosis: Viral ... Pregnancy #hepatology
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
- Differential ... Diagnosis Algorithm ... - If both are normal ... function may be abnormal ... #hepatology
Abnormal liver function tests algorithm. This figure details the initial response to abnormal liver blood tests.
Abnormal liver function ... initial response to abnormal ... *Abnormal USS may ... #LFTs #Abnormal ... #Algorithm #Hepatology
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison Hodgkin's Lymphoma: • Epidemiology: young adults 20-30, older 50-70 •
the spleen or liver ... also arise in normal ... #oncology #diagnosis ... #differential # ... hematology
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
wasting PBC Labs ... • ALT & AST normal ... • Bilirubin - Normal ... bile ducts Differential ... #workup #hepatology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
: • Labs: leukocytosis ... initiation • Differential ... 500 mg QD until normal ... #management #hematology ... #oncology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia Clinical ... syndrome (MDS) (normal ... megakaryocytes and a normal ... #hematology #diagnosis ... #management
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Hodgkin Lymphoma - Clinical ... products that define normal ... Immunohistochemical studies (to differentiate ... classification #hematology ... #oncology #management
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