147 results
Patterns of Liver Injury
Transaminase Levels:
  > 50x normal - Ischemic Hepatitis
  > 20x normal
- Acute Viral Hepatitis ... 10-20x normal ... AST:ALT < 1 - Viral ... Liver #Injury #hepatology ... transaminitis #differential
Causes of Severe Acute Liver Injury
 - Ichemic hepatitis
 - Acute biliary obstruction
 - Drug-Induced liver
Injury - Ichemic hepatitis ... liver injury - Viral ... hepatitis - ... Acute #Causes #Differential ... #Hepatology #Diagnosis
Elevated Transaminases / Transaminitis - Differential Diagnosis

 • Infectious: HAV, HCV, HEV, EBV, HSV, CMV
 •
Transaminitis - Differential ... , Portal vein thrombosis ... • Autoimmune hepatitis ... #Differential # ... Diagnosis #causes #hepatology
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
Liver Enzymes - Differential ... disease US — Normal ... • Alcoholic hepatitis ... Others #LFTs #Hepatology ... #LiverEnzymes #Differential
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework
Mild (<100-500): 
 • NAFLD
 • Cirrhosis
 •
Tests (LFTs) - Differential ... Hepatitis Moderate ... Hepatitis Severe ... #Tests #LFTs #Differential ... #Diagnosis #hepatology
Portal Hypertension - Differential Diagnosis
Portal Pressure = the pressure difference between the pressure in the portal
- Differential ... HTN Signs of portal ... and hepatorenal syndrome ... Cirrhosis/acute hepatitis ... Diagnosis #causes #hepatology
Isolated Hyperbilirubinemia - Differential Diagnosis Algorithm
Direct Hyperbilirubinemia: Dubin-Johnson Syndrome, Rotor Syndrome
Indirect Hyperbilirubinemia: 
 - Trauma, Hematoma,
Hyperbilirubinemia - Differential ... , Rotor Syndrome ... Reticulocyte Count Normal ... Hyperbilirubinemia #Isolated #Differential ... Diagnosis #Algorithm #hepatology
Causes of Acute Liver Injury - Differential Diagnosis
Hepatocellular - Liver Parenchyma
 • Infectious: Hepatitis C, A,
Liver Injury - Differential ... obstruction, HELLP Syndrome ... Infectious: Sepsis, Viral ... Liver #Injury #Differential ... Acute #algorithm #hepatology
Hepatomegaly - Differential Diagnosis Algorithm
Malignant
 • Primary Carcinoma
 • Metastases
 • Lymphoma
 • Leukemia
 • Polycythemia
Hepatomegaly - Differential ... • Budd-Chiari Syndrome ... Infectious • Hepatitis ... #Hepatomegaly #Differential ... Algorithm #Causes #Hepatology
Common Etiologies of Cirrhosis

Inflammation

 - Hepatitis B (15 percent)

 - Hepatitis C (47 percent)

 - Schistosomiasis
Inflammation - Hepatitis ... 15 percent) - Hepatitis ... disease (Budd-Chiari syndrome ... #Diagnosis #Differential ... #Hepatology #Cirrhosis