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diagnosis signs symptoms erythematosus lupus sle antinxp2 arteritis behcet classification common cvid dermatology dermatomyositis differential disease gca giantcell hematology hypogammaglobulinemia
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Clinical Features ... effusion, Restrictive lung ... Demyelinating syndromes ... Endocarditis, Aortic ... erythematosus #signs
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... ) Suspect: Clinical ... Non-autoimmune rheumatologic ... Clinical Features ... Erythematosus #Diagnosis #Rheumatology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
Systemic disease ... (Clinical Dx). ... #diagnosis #management ... #signs #symptoms ... #rheumatology #
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
- Recurrent oral ... • Cogan Syndrome ... purpura: strong sign ... LFT • ESR • ANA ... differential #diagnosis #rheumatology
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
to 8 years Clinical ... • Chronic lung ... hemolytic anemia) • Systemic ... levels are within normal ... : • Nephrotic syndrome
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
those coming off aorta ... Diagnosis = clinical ... 50 in GCA, but normal ... them, but urgent rheumatology ... Symptoms #Diagnosis #Management
Multiple Sclerosis - Summary Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
central nervous system ... • Or brainstem syndromes ... patients with clinically ... stimulation Clinical ... sclerosis #diagnosis #management
Sarcoidosis - Diagnosis and Management Summary Epidemiology 1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
Diagnosis and Management ... granulomas within the lungs ... the lymphatic system ... renal failure Clinical ... #Signs #Symptoms
Anti-NXP-2 Dermatomyositis What? DM with generalized subcutaneous edema Pts have more myalgias, more severe weakness, and an increased prevalence
chest (in a V-sign ... auricular papules Clinical ... Non-small-cell lung ... #diagnosis #management ... #rheumatology #
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
salivary ducts Clinical ... MALT Lymphoma • Lung ... Pharmacologic: • Severe oral ... #Rheumatology # ... Diagnosis #Management
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