6 results
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... fever, myalgias, HoTN ... initiation • Differential ... 500 mg QD until normal ... #APML #diagnosis
Primary and Secondary Causes of Hypertension - Differential Diagnosis Algorithm
Primary (Essential) (95%) - Onset between age
Mislabelled - Repeatedly normal ... taken at home, work ... excess (Cushing syndrome ... Primary #Secondary #HTN ... #Cardiology #Differential
Hypertensive Disorders of Pregnancy
Chronic Hypertension:
 • Guidelines as SBP ≥130 or DBP ≥ 90 mmHg
 •
patients • HELLP: Syndrome ... meds • New onset ... so have high clinical ... #obstetrics #cardiology ... #differential #
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... Workup: • Complete ... blood count with differential ... progression to AML ... #diagnosis #hematology
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
thrombosis+Pulm HTN ... Cryoglobulinemic, Hypo/normo-complementemic ... Paraproteinemias #Hematology ... #Monoclonal #Differential ... #Diagnosis #Oncology
Peripartum Cardiomyopathy - Summary
1. Definition
 • Towards the end of pregnancy to 5 months postpartum
Differential Diagnosis ... predisposition (TTN ... Clinical • Under-recognized ... sx overlap with normal ... #management #cardiology