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oncology algorithm blood china classification disorders erythematosus gap globulin hodgkins lupus management markers mds mnemonic monoclonal myelodysplasia myelodysplastic paraproteinemias plasmacytoma
Blood Disorders - Markers and Differential Diagnosis Algorithm Acute • Myloid (AML) - CD13, CD33, CD34,
- Markers and Differential ... Diagnosis Algorithm ... , Auer rod • Lymphoid ... Pelger-Huet, Macrocytic anemia ... Blood #Disorders #hematology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Weight loss • Anemia ... products that define normal ... Workup: • Full ... Immunohistochemical studies (to differentiate ... #hematology #oncology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... Workup: • Complete ... blood count with differential ... Myelodysplastic #Syndromes #diagnosis ... #hematology #oncology
CHINA Mnemonic for Causes of Splenomegaly C - Congestion (portal hypertension) H - Hematologic (sickle cell, hemolytic anemia) I
hypertension) H - Hematologic ... (sickle cell, hemolytic ... anemia) I - Infection ... Neoplasm (CML, lymphoma ... #Diagnosis #Spleen
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
Cryoglobulinemic, Hypo/normo-complementemic ... (-) hemolytic anemia ... Paraproteinemias #Hematology ... #Monoclonal #Differential ... #Diagnosis #Oncology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
permanent alopecia Differential ... Angioimmunoblastic T-cell ... lymphoma • Evans ... lymphopenia, low PLT • Anemia ... : • Chronic B-cell
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
Albumin > 4) Work-up ... anemia • Other ... light chain • Normal ... Gap #ProteinGap #differential ... #diagnosis #hematology
Solitary Cell Plasmacytoma What? • Plasma cell neoplasms can present as a single lesion (solitary plasmacytoma) • In 3%
mainly in the oral ... Diagnosis? ... • No CRAB - no anemia ... • Non-Hodgkin Lymphoma ... #Workup #Hematology
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