19 results
Summary of Coagulation Deficiencies
Inherited:
 • Hemophilia A - Deficiency of Factor VIII
 • Hemophilia B -
Summary of Coagulation ... Medications - Heparin ... ) • Advanced Liver ... Summary #table #comparison ... #diagnosis #hematology
Liver Disease in Pregnancy
Intrahepatic Cholestasis of Pregnancy (ICP)
 • Onset/Trimester: 25-32 weeks
 • Typical clinical features:
weeks • Typical clinical ... imaging: Normal ... • Histology: Normal-mild ... Disease #Pregnancy #hepatology ... obstetrics #hepatitis #comparison
Appearance of Liver Lesions on Various Imaging Modalities
 • Computed Tomography (CT) - Arterial Phase, Portal
Appearance of Liver ... , Metastasis #Liver ... #Lesions #Hepatic ... differential #diagnosis #comparison ... table #appearance #hepatology
Appearance of Liver Lesions on Computed Tomography (CT) - Arterial Phase, Portal Venous Phase and Delayed
Appearance of Liver ... Arterial Phase, Portal ... #Lesions #Hepatic ... differential #diagnosis #comparison ... table #appearance #hepatology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
organ damage Clinical ... Thrombocytopenia - Normal ... DIC • Severe Liver ... - APTT < 1.5 x normal ... treatment #management #hematology
Portal Hypertension - Differential Diagnosis
Portal Pressure = the pressure difference between the pressure in the portal
>10 mmHg - clinically ... g/dl (suggest hepatic ... sarcoidosis) • Liver ... metastasis • Fatty liver ... Diagnosis #causes #hepatology
Portal venous gas on hepatic ultrasound: A concerning finding in the critically ill patient that should
on hepatic ultrasound ... of air in the hepatic ... venousgas #ultrasound #hepatology ... #liver #pocus # ... clinical #air
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
vascular disorders, coagulation ... deficiency • Liver ... Decreased Support Of Dermal ... Cholesterol emboli • Septic ... Differential #Diagnosis #hematology
Causes of Abnormal PT and/or aPTT
Prolonged Prothrombin Time (PT)
1. Acquired deficiency of FVII
Causes of Abnormal ... Early liver disease ... Reduced liver synthesis ... #differential #hematology ... #coagulation
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
- If both are normal ... • Albumin • Coagulation ... replaced by non-hepatic ... of ALP • Near normal ... #differential #Hepatology