20 results
A non-subtle example of true Sezary syndrome.  Patient presented with erythroderma without antecedent history of
of true Sezary syndrome ... mjcascio #Sezary #Syndrome ... #Cells #Clinical ... #Pathology #Smear ... #Microscopy #Hematology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
Blood Smear • ... Myelodysplastic Syndromes ... Liver Function ... Liver Function ... Algorithm #Causes #Hematology
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
Drug-associated, PCH, Evans Syndrome ... Defects, Drugs, Liver ... Peripheral Blood Smear ... ↑ abnormal RBCs ... Differential #Diagnosis #hematology
Autoagglutination should also be distinguished from “Rouleaux formation” wherein normal blood tends to form stacks on
formation” wherein normal ... dilution with normal ... #Clinical #Pathology ... #Blood #Smear # ... Rouleaux #Formation #Hematology
Liver Disease in Pregnancy
Intrahepatic Cholestasis of Pregnancy (ICP)
 • Onset/Trimester: 25-32 weeks
 • Typical clinical features:
weeks • Typical clinical ... Hepatic imaging: Normal ... • Histology: Normal-mild ... necrosis HELLP Syndrome ... Disease #Pregnancy #hepatology
Portal Hypertension - Differential Diagnosis
Portal Pressure = the pressure difference between the pressure in the portal
>10 mmHg - clinically ... and hepatorenal syndrome ... • Budd Chiari syndrome ... sarcoidosis) • Liver ... Diagnosis #causes #hepatology
Megaloblastic neutrophils in bone marrow.

So-called "giant bands" and "giant metamyelocytes" (blue circles) are 1.5-2 times the
times the size of normal ... neutrophils #BoneMarrow #Smear ... #Hematology #Pathology ... #Clinical
Abnormal liver function tests algorithm.
 This figure details the initial response to abnormal liver blood tests.
Abnormal liver function ... evaluation of the clinical ... /or suspicious clinical ... presence of metabolic syndrome ... #Algorithm #Hepatology
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... Peripheral Smear ... Workup: • Complete ... Peripheral blood smear ... #diagnosis #hematology
Inherited Non-hemolytic Disorders of Hyperbilirubinemia 

== Disorders of Conjugation ==
Gilbert Syndrome:
 • 5-10% of the population
hyperbilirubinemia syndrome ... of about 30% of normal ... of hemolysis or liver ... as jaundice on clinical ... Congenital #bilirubin #hepatology