9 results
Acute promyelocytic leukemia (blood). Typical morphologic features are bilobed ("butterfly") nuclei with dispersed chromatin, subtle to
Acute promyelocytic ... leukemia (blood ... #APL #APML #Pathology ... #Hematology #Clinical ... #Smear
Plasma cell leukemia with extensive rouleaux formation. Aggressive disease & patients typically younger than other forms
Plasma cell leukemia ... with extensive rouleaux ... #rouleaux #formation ... #Clinical #Smear ... #Hematology #Pathology
Hypersegmented neutrophil in a case of acute myeloid leukemia.

Dysplastic neutrophils are typically hypolobated but can be
neutrophil in a case of acute ... myeloid leukemia ... #neutrophils #AML ... #Clinical #Hematology ... #Pathology #Smear
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
APML, CLL Acute ... peripheral blood smear ... ALL (Acute Lymphoblastic ... • Peripheral smear ... #Hematology #Oncology
Autoagglutination should also be distinguished from “Rouleaux formation” wherein normal blood tends to form stacks on
formation” wherein normal ... dilution with normal ... #Clinical #Pathology ... #Blood #Smear # ... #Formation #Hematology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Orange or Hep C Clinical ... • Peripheral smear ... ’s lymphoma or acute ... diagnosis #workup #oncology ... #hematology
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison

Hodgkin's Lymphoma:
 • Epidemiology: young adults 20-30, older 50-70
 •
Autoimmune diseases • Clinical ... involved) • No leukemic ... Malignancies (eg CML, ALL ... NonHodgkins #comparison #oncology ... #differential #hematology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
malignancy (Especially acute ... promyelocytic leukemia ... organ damage Clinical ... • Peripheral smear ... treatment #management #hematology
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Peripheral Smear ... • Hairy Cell Leukemia ... Peripheral blood smear ... Syndromes #diagnosis #hematology ... #oncology