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diagnosis differential algorithm liver abnormal biliary causes chemistry cholangitis elevated hepatopulmonary hps injury interpretation liverenzymes liverfunctiontests patterns primary rvalue syndrome
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis Hepatocellular Pattern (ALT or AST > ALP):
AST): • US - Normal ... Congenital, Others, Cirrhosis ... Burak @kwburak #LFTs ... #Transaminitis ... Algorithm #diagnosis #hepatology
Patterns of Liver Injury Transaminase Levels: > 50x normal - Ischemic Hepatitis > 20x normal
Levels: > 50x normal ... Hepatitis > 20x normal ... CMV), Alcoholic cirrhosis ... Liver #Injury #hepatology ... #LFTs #transaminitis
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
Primary Biliary Cirrhosis ... Pathophysiology ... • ALT & AST normal ... • Bilirubin - Normal ... diagnosis #workup #hepatology
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
disease US — Normal ... Bile Ducts • PSC ... Infiltrative • Cirrhosis ... • Others #LFTs ... #Hepatology #LiverEnzymes
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Interpretation of LFTs ... - If both are normal ... hepatitis: < 1 • Cirrhosis ... #differential #Hepatology ... #transaminitis
Hepatopulmonary Syndrome - Illness Script HPS is a pulmonary disorder of chronic liver disease characterized by a
abnormalities PATHOPHYSIOLOGY ... overperfusion + decreased RBC ... • Stigmata of cirrhosis ... Liver disease &/or portal ... #diagnosis #hepatology
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