17 results
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA)

Skin involvement in granulomatosis with polyangiitis (GPA) is common and
disease or more commonly ... Maculopapular rash ... • Goodpasture syndrome ... Polyangiitis #GPA #dermatology ... #rash #diagnosis
Secondary Syphilis Rash
Secondary syphilis is the most contagious of all the stages of this disease, and
commonly characterize ... genital, anal or oral ... reddish brown spots ... #Diagnosis #Clinical ... #Photo #Dermatology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... • Incidence: common ... 500 mg QD until normal ... Differentiation #Syndrome ... #management #hematology
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS)
Definition: 
 • Severe adverse drug reaction, characterized by
extensive skin rash ... Oral/IV Glucocorticoids ... SinaiBmoreIMRes #DRESS #Syndrome ... #dermatology #diagnosis ... #management
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
levels are within normal ... : • Nephrotic syndrome ... (Epstein-Barr syndrome ... hypogammaglobulinemia #immunology #hematology ... #diagnosis #management
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Overwhelming clinical syndrome ... symptoms can mimic common ... • Infection should ... #management #treatment ... #hematology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Differential Diagnosis ... - spares nasolabial ... Kidney disease common ... flares • CRP normal ... Erythematosus #Diagnosis
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework

== Quantitative or Qualitative defect in
- Differential Diagnosis ... von Willebrand syndrome ... of factor VII should ... defects in the common ... #Hematology
Hepatopulmonary Syndrome - Diagnosis and Management Summary
A defect in arterial oxygenation due to a gas exchange
Hepatopulmonary Syndrome ... • Dyspnea - Common ... Should be performed ... hepatopulmonary #syndrome ... #diagnosis #management
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
anterior chest wall, parts ... • A clinical diagnosis ... palmoplantar pustulosis: oral ... diagnosis #management ... #Dermatology